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Drug interactions with tenofovir disoproxil fumarate oral and sitagliptin-metformin oral

tenofovir disoproxil fumarate oral brand names and other generic formulations include:

Viread Oral

All generic drug interactions for tenofovir disoproxil fumarate oral (lists will include brand and generic names):

sitagliptin-metformin oral brand names and other generic formulations include:

Janumet Oral, Janumet XR Oral

All generic drug interactions for sitagliptin-metformin oral (lists will include brand and generic names):
Significant - Monitor CloselyPotential for interaction

tenofovir disoproxil fumarate oral and sitagliptin-metformin oral

tenofovir disoproxil fumarate oral increases levels of sitagliptin-metformin oral by reducing drug clearance through the kidneys. Combination increases the level of acid in the body (lactic acidosis).

Patient Drug Interactions Source: RxList
© 2014 RxList, Inc.
Significant - Monitor CloselyPotential for interaction, monitor.

tenofovir disoproxil fumarate oral and sitagliptin-metformin oral

tenofovir disoproxil fumarate oral increases levels of sitagliptin-metformin oral by decreasing renal clearance. Increased risk of lactic acidosis.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2014 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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