Dtic-Dome (Dacarbazine) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Dtic-Dome

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Cancer is the uncontrolled growth of abnormal cells anywhere in a body. The abnormal cells are termed cancer cells, malignant cells, or tumor cells. Many cancers and the abnormal cells that compose the cancer tissue are further identified by the name of the tissue that the abnormal cells originated from (for example, breast cancer, lung cancer, colon cancer). Cancer is not confined to humans; animals and other living organisms can get cancer. Below is a schematic that shows normal cell division and how when a cell is damaged or altered without repair to its system, the cell usually dies. Also shown is what can occur when such damaged or unrepaired cells do not die and become cancer cells and proliferate with uncontrolled growth; a mass of cancer cells develop. Frequently, cancer cells can break away from this original mass of cells, travel through the blood and lymph systems, and lodge in other organs where they can again repeat the ...

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Dtic-Dome

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Dtic-Dome Patient Information Including Side Effects

Brand Names: Dtic-Dome

Generic Name: dacarbazine (Pronunciation: da CARB ah zine )

What is dacarbazine (Dtic-Dome)?

Dacarbazine is a cancer (antineoplastic) medication. Dacarbazine interferes with the growth of cancer cells and slows their growth and spread in the body.

Dacarbazine is used to treat skin cancer (malignant melanoma) and Hodgkin's Disease.

Dacarbazine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of dacarbazine (Dtic-Dome)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); or
severe nausea, vomiting, diarrhea, or loss of appetite.

Other less serious side effects may be more likely to occur. Talk to your doctor if you experience:

temporary hair loss;
facial flushing or numbness;
hives, itching and rash;
mild to moderate diarrhea;
mild to moderate nausea, vomiting, or loss of appetite; or
flu-like symptoms including fever, muscle and joint pain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dacarbazine (Dtic-Dome)?

Dacarbazine should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of dacarbazine including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection such as fever; chills, or sore throat); liver problems; severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with dacarbazine.

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