Duac Topical Gel
Duac Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Duac (clindamycin phosphate and benzoyl peroxide) Gel is used to treat acne. It is a combination of clindamycin, an antibiotic, and benzoyl peroxide, an antibacterial that also has a mild drying effect. Common side effects include dry skin, redness, burning, itching, or skin peeling.
Duac Gel topical (for the skin) is applied in a once daily dose as directed by a physician to affected areas after the skin is gently washed, rinsed with warm water and patted dry. Duac may interact with topical or oral erythromycin. Other drugs may interact with Duac. Tell your doctor about all the prescription and over-the-counter medications and supplements you use. During pregnancy, Duac should be used only when prescribed. This drug may pass into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Our Duac (clindamycin phosphate and benzoyl peroxide) Gel Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Duac in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have any of these serious side effects:
- severe redness, burning, stinging, or peeling of treated skin areas; or
- diarrhea that is watery or bloody.
Less serious side effects may include:
- mild burning or stinging;
- itching or tingly feeling;
- dryness or peeling of treated skin; or
- redness or other irritation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Duac (Clindamycin Benzoyl Peroxide) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Duac Overview - Patient Information: Side Effects
You can use skin moisturizing creams or lotions to help reduce many of the side effects listed above.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This medication may be absorbed into your bloodstream and very rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Duac (Clindamycin Benzoyl Peroxide)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Duac FDA Prescribing Information: Side Effects
(Adverse Reactions)
SIDE EFFECTS
During clinical trials, all patients were graded for facial erythema, peeling, burning, and dryness on the following scale: 0 = absent, 1 = mild, 2 = moderate, and 3 = severe. The percentage of patients that had symptoms present before treatment (at baseline) and during treatment were as follows:
Local reactions with use of DUAC® Gel % of patients using
DUAC® Gel with symptom present Combined results from 5 studies (n = 397)
| Before Treatment (Baseline) | During Treatment | |||||
| Mild | Moderate | Severe | Mild | Moderate | Severe | |
| Erythema | 28% | 3% | 0 | 26% | 5% | 0 |
| Peeling | 6% | < 1% | 0 | 17% | 2% | 0 |
| Burning | 3% | < 1% | 0 | 5% | < 1% | 0 |
| Dryness | 6% | < 1% | 0 | 15% | 1% | 0 |
(Percentages derived by # subjects with symptom score/# enrolled DUAC® Gel subjects, n = 397).
Anaphylaxis, as well as allergic reactions leading to hospitalization, has been reported in post-marketing use with DUAC® Gel. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Read the entire FDA prescribing information for Duac (Clindamycin Benzoyl Peroxide) »
Additional Duac Topical Gel Information
Duac Topical Gel - User Reviews
Duac Topical Gel User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Duac Topical Gel sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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