"Miriam E. Tucker
Medscape Medical News
The US Food and Drug Administration has approved the empagliflozin/linagliptin combination Glyxambi (Boehringer Ingelheim/Eli Lilly) as adjunctive treatment to diet and "...
Duetact Patient Information including If I Miss a Dose
In this Article
- What is glimepiride and pioglitazone (Duetact)?
- What are the possible side effects of glimepiride and pioglitazone (Duetact)?
- What is the most important information I should know about glimepiride and pioglitazone (Duetact)?
- What should I discuss with my health care provider before taking glimepiride and pioglitazone (Duetact)?
- How should I take glimepiride and pioglitazone (Duetact)?
- What happens if I miss a dose (Duetact)?
- What happens if I overdose (Duetact)?
- What should I avoid while taking glimepiride and pioglitazone (Duetact)?
- What other drugs will affect glimepiride and pioglitazone (Duetact)?
- Where can I get more information?
What happens if I miss a dose (Duetact)?
Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Duetact)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A glimepiride and pioglitazone overdose can cause life-threatening hypoglycemia. Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking glimepiride and pioglitazone (Duetact)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
Avoid exposure to sunlight or tanning beds. Glimepiride and pioglitazone can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
What other drugs will affect glimepiride and pioglitazone (Duetact)?
Tell your doctor about all other medicines you use, especially:
- gemfibrozil (Lopid);
- rifampin (Rifadin, Rimactane, Rifater); or
- fluconazole (Diflucan), ketoconazole (Nizoral).
Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use any of the following:
- albuterol (Proventil, Ventolin);
- clonidine (Catapres);
- reserpine; or
- beta-blockers such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others.
You may be more likely to have hyperglycemia (high blood sugar) if you take glimepiride and pioglitazone with:
- diuretics (water pills);
- steroids (prednisone and others);
- niacin (Advicor, Niaspan, Niacor, Niaspan, Simcor, Slo-Niacin, and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others); and
- diet pills or medicines to treat asthma, colds or allergies.
You may be more likely to have hypoglycemia (low blood sugar) if you take glimepiride and pioglitazone with:
- exenatide (Byetta);
- probenecid (Benemid);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- a blood thinner such as warfarin (Coumadin, Jantoven);
- sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others);
- a monoamine oxidase inhibitor (MAOI); and
- other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).
These lists are not complete and there are many other medicines that can increase or decrease the effects of glimepiride and pioglitazone on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about glimepiride and pioglitazone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Duetact Information
Duetact - User Reviews
Duetact User Reviews
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