Recommended Topic Related To:

Duoneb

"The U.S. Food and Drug Administration today approved Breo Ellipta (fluticasone furoate and vilanterol inhalation powder) for the long-term, once-daily, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary di"...

Duoneb

Duoneb

Duoneb Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

DuoNeb (ipratropium bromide and albuterol sulfate) is used to treat and prevent symptoms (wheezing and shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema). This product contains 2 medications: ipratropium and albuterol (salbutamol). Both drugs are bronchodilators. Common side effects include headache, dizziness, nausea, dry mouth, shaking (tremors), or nervousness.

The recommended dose of DuoNeb is one 3 mL vial administered 4 times per day via nebulization with up to 2 additional 3 mL doses allowed per day, if needed. DuoNeb may interact with certain beta-blockers, such as propranolol. Drug interactions may change how your medications work or increase your risk for serious side effects. Tell your doctor all the products you use, including prescription/nonprescription drugs and herbal products. Do not start, stop, or change the dosage of any medicines without your doctor's approval. During pregnancy, DuoNeb should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Our DuoNeb (ipratropium bromide and albuterol sulfate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Duoneb in Detail - Patient Information: Side Effects

Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using albuterol and ipratropium and call your doctor at once if you have any of these serious side effects:

  • bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
  • chest pain and fast, pounding, or uneven heart beats;
  • swelling of your ankles or feet;
  • vision problems, eye pain, or seeing halos around lights;
  • pain or burning with urination; or
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

Less serious side effects may include:

  • hoarse voice, sore throat, cough, runny or stuffy nose;
  • constipation, diarrhea;
  • nausea, upset stomach;
  • headache; or
  • leg cramps.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Duoneb (Ipratropium Bromide and Albuterol Sulfate) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Duoneb Overview - Patient Information: Side Effects

SIDE EFFECTS: See also How to Use section.

Headache, dizziness, nausea, dry mouth, shaking (tremors), nervousness, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Infrequently, this medication may cause severe sudden worsening of breathing problems right after use. If you have sudden worsening of breathing, get medical help right away.

Tell your doctor right away if you have any serious side effects, including: eye pain, difficult/painful urination, vision changes (such as blurred vision, seeing halos), muscle cramps.

Get medical help right away if you have any serious side effects, including: chest pain, fast/pounding/irregular heartbeat, rapid breathing, confusion.

A very serious allergic reaction to this product is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Duoneb (Ipratropium Bromide and Albuterol Sulfate)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Duoneb FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Adverse reaction information concerning DuoNeb (ipratropium bromide and albuterol sulfate) was derived from the 12-week controlled clinical trial.

ADVERSE EVENTS OCCURRING IN ≥ 1% OF ≥ 1 TREATMENT GROUP(S) AND WHERE THE COMBINATION TREATMENT SHOWED THE HIGHEST PERCENTAGE

Body System COSTART Term Albuterol
n (%)
Ipratropium
n (%)
DuoNeb
n (%)
NUMBER OF PATIENTS 761 754 765
N (%) Patients with AE 327 (43.0) 329 (43.6) 367 (48.0)
BODY AS A W HOLE
  Pain 8 (1.1) 4 (0.5) 10 (1.3)
  Pain chest 11 (1.4) 14 (1.9) 20 (2.6)
DIGESTIVE
  Diarrhea 5 (0.7) 9 (1.2) 14 (1.8)
  Dyspepsia 7 (0.9) 8 (1.1) 10 (1.3)
  Nausea 7 (0.9) 6 (0.8) 11 (1.4)
MUSCULO-SKELETAL
  Cramps leg 8 (1.1) 6 (0.8) 11 (1.4)
RESPIRATORY
  Bronchitis 11 (1.4) 13 (1.7) 13 (1.7)
  Lung Disease 36 (4.7) 34 (4.5) 49 (6.4)
  Pharyngitis 27 (3.5) 27 (3.6) 34 (4.4)
  Pneumonia 7 (0.9) 8 (1.1) 10 (1.3)
UROGENITAL
  Infection urinary tract 3 (0.4) 9 (1.2) 12 (1.6)

Additional adverse reactions reported in more than 1% of patients treated with DuoNeb (ipratropium bromide and albuterol sulfate) included constipation and voice alterations.

In the clinical trial, there was a 0.3% incidence of possible allergic-type reactions, including skin rash, pruritus, and urticaria.

Additional information derived from the published literature on the use of albuterol sulfate and ipratropium bromide singly or in combination includes precipitation or worsening of narrow-angle glaucoma, acute eye pain, blurred vision, paradoxical bronchospasm, wheezing, exacerbation of COPD symptoms, drowsiness, aching, flushing, upper respiratory tract infection, palpitations, taste perversion, elevated heart rate, sinusitis, back pain, sore throat, and metabolic acidosis. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Read the entire FDA prescribing information for Duoneb (Ipratropium Bromide and Albuterol Sulfate) »

A A A

Duoneb - User Reviews

Duoneb User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Duoneb sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations