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Durezol Patient Information Including Side Effects

Brand Names: Durezol

Generic Name: difluprednate ophthalmic (Pronunciation: DYE floo PRED nate off THAL mik)

What is difluprednate ophthalmic (Durezol)?

Difluprednate is a steroid medicine. It prevents the release of substances in the body that cause inflammation.

Difluprednate ophthalmic (for the eye) is used to treat eye swelling caused by surgery.

Difluprednate ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of difluprednate ophthalmic (Durezol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • pain behind your eyes, sudden vision changes, severe headache;
  • sudden eye irritation;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights; or
  • signs of new eye infection, such as swelling, draining, or crusting of your eyes.

Less serious side effects may include mild burning, stinging, or itching of your eyes.

  • feeling like something is in your eye;
  • eyes being more sensitive to light;
  • eye pain, itching, or redness; or
  • itchy or watery eyes.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Durezol (difluprednate opthalmic emulsion) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about difluprednate ophthalmic (Durezol)?

You should not use this medication if you are allergic to difluprednate, or if you have any type of viral or fungal eye infection, ocular herpes, or an untreated infection in your eye or elsewhere, including chickenpox.

Before using difluprednate ophthalmic, tell your doctor if you are allergic to any drugs, or if you have herpes. You may need a dose adjustment or special tests to safely use difluprednate.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not stop using difluprednate suddenly without first talking to your doctor. Tell your doctor if your symptoms do not improve after 2 days of treatment with difluprednate ophthalmic.

Do not wear any contact lens that has not been approved by your doctor.

Do not use difluprednate ophthalmic while you are wearing regular contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses and cause discoloration. Wait at least 15 minutes after using difluprednate before putting your contact lenses in.

Do not use any other eye medications unless your doctor has prescribed them.

Side Effects Centers

Durezol - User Reviews

Durezol User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Durezol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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