May 24, 2017
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"SYDNEY, AUSTRALIA ” A small randomized trial reports sharp blood-pressure reductions in untreated hypertensives using a single pill combining four BP-lowering drugs at one-quarter the usual dose.

Among 18 patients, mean 24-hour systol"...




Avoid Abrupt Discontinuation

Advise patients to take DUTOPROL regularly and continuously, as directed. If a dose is missed, instruct the patient to take only the next scheduled dose (without doubling the dose). Instruct patients not to interrupt or discontinue DUTOPROL without consulting a healthcare provider. [See BOXED WARNING and WARNINGS AND PRECAUTIONS].


Inform patients that beta adrenergic blockers can cause bronchospasm and to inform their healthcare providers if they start to wheeze or have difficulty breathing.[See WARNINGS AND PRECAUTIONS]

Electrolyte Changes

Inform patients that they may need blood tests to monitor their serum electrolytes. [See WARNINGS AND PRECAUTIONS].

Acute Myopia And Secondary Angle-Closure Glaucoma

Inform patients to report decreased visual acuity or ocular pain and to stop DUTOPROL and contact their healthcare provider right away if these symptoms occur. [See WARNINGS AND PRECAUTIONS].

Hypersensitivity Reaction

Instruct patients that hypersensitivity reactions to DUTOPROL may occur. [See CONTRAINDICATIONS].

Lithium Toxicity

Instruct patients to inform other doctors that they are taking a diuretic. [See DRUG INTERACTIONS].

Last reviewed on RxList: 12/6/2016
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Get tips on handling your hypertension.