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Dyazide Patient Information Including Side Effects

Brand Names: Dyazide, Maxzide, Maxzide-25

Generic Name: hydrochlorothiazide and triamterene (Pronunciation: HYE dro klor oh THY a zide and trye AM ter een)

What is hydrochlorothiazide and triamterene (Dyazide)?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Triamterene is a potassium-sparing diuretic that also prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

The combination of hydrochlorothiazide and triamterene is used to treat fluid retention (edema) and high blood pressure (hypertension).

Hydrochlorothiazide and triamterene may also be used for purposes not listed in this medication guide.


capsule, red/white, imprinted with DYAZIDE SB

HCT-Triamterene 25 mg-37.5 mg Cap-GG

capsule, white, imprinted with GG 606

HCT-Triamterene 25 mg-37.5 mg Tab-BAR

rectangular, orange, imprinted with PLIVA 534

HCT-Triamterene 25 mg-37.5 mg Tab-GG

round, green, imprinted with GG 165

HCT-Triamterene 50 mg-75 mg Tab-GG

round, yellow, imprinted with GG 172

HCTZ-Tramterene 50 mg-25 mg-IVA

capsule, red, imprinted with Z 2950

HCTZ-Triam 37.5-25 mg-GG

capsule, white, imprinted with GG 606

HCTZ-Triam 37.5-25 mg-MYL

capsule, green/yellow, imprinted with MYLAN 2537

HCTZ-Triam 37.5-25-MYL

round, green, imprinted with TH 1, MYLAN

HCTZ-Triam 50-25-GG

capsule, red, imprinted with GG 580

HCTZ-Triam 75-50-MYL

round, yellow, imprinted with MYLAN, TH 2

HCTZ-Triamterene 25 mg-37.5 mg Cap

white, imprinted with 488, DPI

HCTZ-Triamterene 25 mg-37.5 mg Tab

oval, green, imprinted with barr, 555 643

HCTZ-Triamterene 50 mg-75 mg

oval, yellow, imprinted with barr, 555 444


bowtie, yellow, imprinted with BM8, MAXZIDE


bowtie, green, imprinted with BM9, MAXZIDE

Triamterene-HCTZ 37.5-25 mg-WAT

round, green, imprinted with WATSON 424

Triamterene-HCTZ 75-50 mg-WAT

round, yellow, imprinted with WATSON 348

What are the possible side effects of hydrochlorothiazide and triamterene (Dyazide)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using hydrochlorothiazide and triamterene and call your doctor at once if you have a serious side effect such as:

  • eye pain, vision problems;
  • slow, fast, or uneven heartbeat;
  • feeling like you might pass out;
  • swelling or rapid weight gain;
  • urinating less than usual or not at all;
  • headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • high potassium (irregular heart rate, weak pulse, muscle weakness, tingly feeling);
  • severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • mild nausea, diarrhea, constipation;
  • dizziness, headache;
  • blurred vision;
  • dry mouth;
  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Dyazide (hydrochlorothiazide and triamterene) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about hydrochlorothiazide and triamterene (Dyazide)?

You should not use this medication if you are allergic to hydrochlorothiazide or triamterene, or if you have kidney disease, urination problems, high levels of potassium in your blood, or if you are taking other diuretics similar to triamterene. Do not use potassium supplements unless your doctor has told you to.

Before using this medication, tell your doctor if you have heart or liver disease, glaucoma, diabetes, a breathing disorder, gout, lupus, kidney stones, a pancreas disorder, or an allergy to sulfa drugs or penicillin.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and triamterene.

Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.

Do not use potassium supplements, salt substitutes, or low-sodium milk while you are taking hydrochlorothiazide and triamterene, unless your doctor has told you to.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Side Effects Centers

Dyazide - User Reviews

Dyazide User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Dyazide sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Get tips on handling your hypertension.