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Dyazide Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Dyazide (hydrochlorothiazide and triamterene) is used to treat fluid retention (edema) and high blood pressure (hypertension). It is a combination of hydrochlorothiazide, a thiazide diuretic (water pill), and triamterene, a potassium-sparing diuretic. This medication is available in generic form. Common side effects include dizziness, lightheadedness, headache, or upset stomach as your body adjusts to the medication.
The usual dose of Dyazide is one or two capsules given once daily, with monitoring of serum potassium and of the clinical effect. Dyazide may interact with lithium, amphotericin, methenamine, steroids, blood thinners, insulin or oral diabetes medicine, laxatives, ACE inhibitors, indomethacin or other NSAIDs (non-steroidal anti-inflammatory drugs), or other medicines that make you light-headed (such as cold or allergy medicine, narcotics, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Tell your doctor all medications you use. During pregnancy, Dyazide should be used only when prescribed. It is unknown if triamterene passes into breast milk. Hydrochlorothiazide passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Our Dyazide (hydrochlorothiazide and triamterene) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Dyazide in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using hydrochlorothiazide and triamterene and call your doctor at once if you have a serious side effect such as:
- eye pain, vision problems;
- slow, fast, or uneven heartbeat;
- feeling like you might pass out;
- swelling or rapid weight gain;
- urinating less than usual or not at all;
- headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
- low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
- high potassium (irregular heart rate, weak pulse, muscle weakness, tingly feeling);
- severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
- patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
- jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- mild nausea, diarrhea, constipation;
- dizziness, headache;
- blurred vision;
- dry mouth;
- skin rash.
Read the entire detailed patient monograph for Dyazide (Hydrochlorothiazide and Triamterene) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Dyazide Overview - Patient Information: Side Effects
Dizziness, lightheadedness, headache, or upset stomach may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, muscle cramps/weakness, slow/fast/irregular heartbeat, unusual decreased urination, unusual dry mouth/thirst, decrease in vision, eye pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Dyazide (Hydrochlorothiazide and Triamterene)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Dyazide FDA Prescribing Information: Side Effects
Adverse effects are listed in decreasing order of severity.
Renal: Acute renal failure (one case of irreversible renal failure has been reported), interstitial nephritis, renal stones composed primarily of triamterene, elevated BUN, and serum creatinine, abnormal urinary sediment.
Musculoskeletal: Muscle cramps.
Central Nervous System: Weakness, fatigue, dizziness, headache, dry mouth.
Miscellaneous: Impotence, sialadenitis.
Thiazides alone have been shown to cause the following additional adverse reactions:
Central Nervous System: Paresthesias, vertigo.
Ophthalmic: Xanthopsia, transient blurred vision.
Respiratory: Allergic pneumonitis, pulmonary edema, respiratory distress.
Other: Necrotizing vasculitis, exacerbation of lupus.
Neonate and infancy: Thrombocytopenia and pancreatitis-rarely, in newborns whose mothers have received thiazides during pregnancy.
Read the entire FDA prescribing information for Dyazide (Hydrochlorothiazide and Triamterene) »
Additional Dyazide Information
Dyazide - User Reviews
Dyazide User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.