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Dyazide

Last reviewed on RxList: 10/18/2016
Dyazide Side Effects Center

Last reviewed on RxList 10/25/2016

Dyazide (hydrochlorothiazide and triamterene) is a combination of a thiazide diuretic (water pill) and a potassium-sparing diuretic used to treat fluid retention (edema) and high blood pressure (hypertension). Dyazide is available in generic form. Common side effects of Dyazide include:

  • dizziness,
  • lightheadedness,
  • headache, or upset stomach as your body adjusts to the medication.

Other side effects of Dyazide include:

The usual dose of Dyazide is one or two capsules given once daily, with monitoring of serum potassium and of the clinical effect. Dyazide may interact with lithium, amphotericin, methenamine, steroids, blood thinners, insulin or oral diabetes medicine, laxatives, ACE inhibitors, indomethacin or other NSAIDs (non-steroidal anti-inflammatory drugs), or other medicines that make you light-headed (such as cold or allergy medicine, narcotics, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Tell your doctor all medications you use. During pregnancy, Dyazide should be used only when prescribed. It is unknown if triamterene passes into breast milk. Hydrochlorothiazide passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Our Dyazide (hydrochlorothiazide and triamterene) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dyazide Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using hydrochlorothiazide and triamterene and call your doctor at once if you have a serious side effect such as:

  • eye pain, vision problems;
  • slow, fast, or uneven heartbeat;
  • feeling like you might pass out;
  • swelling or rapid weight gain;
  • urinating less than usual or not at all;
  • headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • high potassium (irregular heart rate, weak pulse, muscle weakness, tingly feeling);
  • severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • mild nausea, diarrhea, constipation;
  • dizziness, headache;
  • blurred vision;
  • dry mouth;
  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Dyazide (Hydrochlorothiazide and Triamterene)

Dyazide Professional Information

SIDE EFFECTS

Adverse effects are listed in decreasing order of severity.

Hypersensitivity: Anaphylaxis, rash, urticaria, subacute cutaneous lupus erythematosus-like reactions, photosensitivity.

Cardiovascular: Arrhythmia, postural hypotension.

Metabolic: Diabetes mellitus, hyperkalemia, hypokalemia, hyponatremia, acidosis, hypercalcemia, hyperglycemia, glycosuria, hyperuricemia, hypochloremia.

Gastrointestinal: Jaundice and/or liver enzyme abnormalities, pancreatitis, nausea and vomiting, diarrhea, constipation, abdominal pain.

Renal: Acute renal failure (one case of irreversible renal failure has been reported), interstitial nephritis, renal stones composed primarily of triamterene, elevated BUN, and serum creatinine, abnormal urinary sediment.

Hematologic: Leukopenia, thrombocytopenia and purpura, megaloblastic anemia.

Musculoskeletal: Muscle cramps.

Central Nervous System: Weakness, fatigue, dizziness, headache, dry mouth.

Miscellaneous: Impotence, sialadenitis.

Thiazides alone have been shown to cause the following additional adverse reactions:

Central Nervous System: Paresthesias, vertigo.

Ophthalmic: Xanthopsia, transient blurred vision.

Respiratory: Allergic pneumonitis, pulmonary edema, respiratory distress.

Other: Necrotizing vasculitis, exacerbation of lupus.

Hematologic: Aplastic anemia, agranulocytosis, hemolytic anemia.

Neonate and infancy: Thrombocytopenia and pancreatitis-rarely, in newborns whose mothers have received thiazides during pregnancy.

Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis.

Read the entire FDA prescribing information for Dyazide (Hydrochlorothiazide and Triamterene)

Related Resources for Dyazide

Read the Dyazide User Reviews »

© Dyazide Patient Information is supplied by Cerner Multum, Inc. and Dyazide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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