Ebola Hemorrhagic Fever (Ebola HF) (cont.)
Charles Patrick Davis, MD, PhD
Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
Jerry R. Balentine, DO, FACEP
Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.
In this Article
- Ebola hemorrhagic fever (Ebola virus disease) facts
- What is Ebola hemorrhagic fever?
- What is the history of Ebola hemorrhagic fever?
- What causes Ebola hemorrhagic fever?
- What are risk factors for Ebola hemorrhagic fever?
- What are Ebola virus disease symptoms and signs?
- How do physicians diagnose Ebola hemorrhagic fever?
- What is the treatment for Ebola hemorrhagic fever?
- What are complications of Ebola hemorrhagic fever?
- What is the prognosis of Ebola hemorrhagic fever?
- Is it possible to prevent Ebola hemorrhagic fever? Is there a vaccine for Ebola hemorrhagic fever?
- What is the latest research on Ebola hemorrhagic fever?
- Ebola Virus Slideshow Pictures
- Take the MRSA Quiz!
- Bacterial Infections 101 Slideshow Pictures
- Find a local Doctor in your town
What is Ebola hemorrhagic fever?
Ebola hemorrhagic fever is a viral disease caused by Ebola virus that results in nonspecific symptoms (see symptom section of this article) early in the disease and often causes internal and external hemorrhage (bleeding) as the disease progresses. Ebola hemorrhagic fever is considered one of the most lethal viral infections; the mortality rate (death rate) is very high during outbreaks (reports of outbreaks range from about 50%-100% of humans infected, depending on the Ebola strain); consequently the survival rate may range from about 50% to zero.
What is the history of Ebola hemorrhagic fever?
Ebola hemorrhagic fever was first noted in Zaire (currently, the Democratic Republic of the Congo or DRC) in 1976. The original outbreak was in a village near the Ebola River after which the disease was named. During that time, the virus was identified in person-to-person contact transmission. Of the 318 patients diagnosed with Ebola, 88% died. Since that time, there have been multiple outbreaks of Ebola virus, and five strains have been identified; four of the strains are responsible for the high death rates. The four Ebola strains are termed as follows: Zaire, Sudan, Tai Forest, and Bundibugyo virus, with Zaire being the most lethal strain. A fifth strain termed Reston has been found in the Philippines. The strain infects primates, pigs, and humans and causes few if any symptoms and no deaths in humans. Most outbreaks of the more lethal strains of Ebola have occurred in Africa and mainly in small- or medium-sized towns. Bats, monkeys, and other animals are thought to maintain the virus life cycle in the wild; humans can become infected from handling and/or eating infected animals. Once an Ebola outbreak is recognized, African officials isolate the area until the outbreak ceases. However, in this new outbreak that began in Africa in March 2014, some of the infected patients reached larger city centers before the outbreak was recognized; this caused further spread Ebola. The infecting Ebola virus detected this outbreak is the Zaire strain, the most pathogenic strain of Ebola. Health agencies are terming this outbreak as an "unprecedented epidemic." This epidemic spread quickly in the African countries of Guinea and Sierra Leone. In addition, countries of Liberia, Nigeria, Senegal, and Mali all reported confirmed infections with Ebola. In addition, a very few sporadic infections were noted in the United States, Spain, and the United Kingdom; most of the individuals with Ebola in these countries were either imported infections from Africa or were new infections from treating patients who originally became infected in Africa.
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