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Edecrin

"What are diuretics and how do they work?

The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chlorid"...

Edecrin

Edecrin Side Effects Center

Edecrin (ethacrynic acid) is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. It is a loop diuretic (water pill). Common side effects include dizziness, lightheadedness, headache, blurred vision, stomach upset, mild weakness/tiredness, or diarrhea.

The smallest dose of Edecrin should be given to produce gradual weight loss (about 1 to 2 pounds per day). Onset of diuresis usually occurs at 50 to 100 mg for adults. After diuresis has been achieved, the minimally effective dose (usually from 50 to 200 mg daily) may be given on a continuous or intermittent dosage schedule. Edecrin may interact with lithium, digoxin, blood thinners, other diuretics, steroids, cancer medicines, cephalosporin antibiotics, aspirin and other salicylates, NSAIDs (non-steroidal anti-inflammatory drugs), amikacin, gentamicin, netilmicin, streptomycin, or tobramycin. During pregnancy, Edecrin should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Edecrin (ethacrynic acid) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

Edecrin (ethacrynic acid) is used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. It is a loop diuretic (water pill). Common side effects include dizziness, lightheadedness, headache, blurred vision, stomach upset, mild weakness/tiredness, or diarrhea.

The smallest dose of Edecrin should be given to produce gradual weight loss (about 1 to 2 pounds per day). Onset of diuresis usually occurs at 50 to 100 mg for adults. After diuresis has been achieved, the minimally effective dose (usually from 50 to 200 mg daily) may be given on a continuous or intermittent dosage schedule. Edecrin may interact with lithium, digoxin, blood thinners, other diuretics, steroids, cancer medicines, cephalosporin antibiotics, aspirin and other salicylates, NSAIDs (non-steroidal anti-inflammatory drugs), amikacin, gentamicin, netilmicin, streptomycin, or tobramycin. During pregnancy, Edecrin should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Edecrin (ethacrynic acid) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Edecrin in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using ethacrynic acid and call your doctor at once if you have any of these serious side effects:

  • dry mouth, thirst, nausea, vomiting;
  • feeling weak, drowsy, restless, or light-headed;
  • fast or uneven heartbeat;
  • muscle pain or weakness;
  • easy bruising or bleeding, unusual weakness;
  • fever, chills, body aches, flu symptoms;
  • severe or watery diarrhea;
  • blood in your urine or stools;
  • coughing up blood or vomit that looks like coffee grounds;
  • rapid weight loss;
  • hearing loss, feeling of fullness in the ear; or
  • jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • mild diarrhea, stomach pain, loss of appetite;
  • trouble swallowing;
  • headache; or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Edecrin (Ethacrynic Acid) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Edecrin Overview - Patient Information: Side Effects

SIDE EFFECTS: Dizziness, lightheadedness, headache, blurred vision, stomach upset, mild weakness/tiredness, or diarrhea may occur. This medication will cause an increase in the amount of urine. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This drug is a strong "water pill" (diuretic). Using too much of this drug can lead to serious water and mineral loss (dehydration). Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration: loss of appetite, confusion, severe dizziness/fainting, unusual dry mouth/thirst, severe headache, fast/irregular heartbeat, muscle cramps/spasms, nausea/vomiting, numbness/tingling, seizure, decrease in amount of urine, unusual weakness/tiredness.

Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, black/bloody stools, severe watery diarrhea, signs of infection (e.g., fever, persistent sore throat), ringing in the ear, feeling of spinning (vertigo), hearing loss, mental/mood changes (e.g., extreme sleepiness), pain/redness/new swelling of arms/legs, stomach/abdominal pain, large change in the amount of urine, dark urine, vomit that looks like coffee grounds, yellowing eyes/skin.

Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, weakness on one side of the body, slurred speech, vision changes.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Edecrin (Ethacrynic Acid)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Edecrin FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Gastrointestinal

Anorexia, malaise, abdominal discomfort or pain, dysphagia, nausea, vomiting, and diarrhea have occurred. These are more frequent with large doses or after one to three months of continuous therapy. A few patients have had sudden onset of profuse, watery diarrhea. Discontinue EDECRIN (ethacrynic acid) if diarrhea is severe and do not give it again. Gastrointestinal bleeding has occurred in some patients. Rarely, acute pancreatitis has been reported.

Metabolic

Reversible hyperuricemia and acute gout have been reported. Acute symptomatic hypoglycemia with convulsions occurred in two uremic patients who received doses above those recommended. Hyperglycemia has been reported. Rarely, jaundice and abnormal liver function tests have been reported in seriously ill patients receiving multiple drug therapy, including EDECRIN (ethacrynic acid) .

Hematologic

Agranulocytosis or severe neutropenia has been reported in a few critically ill patients also receiving agents known to produce this effect. Thrombocytopenia has been reported rarely.

Henoch-Schönlein purpura has been reported rarely in patients with rheumatic heart disease receiving multiple drug therapy, including EDECRIN (ethacrynic acid) .

Special Senses (see WARNINGS)

Deafness, tinnitus and vertigo with a sense of fullness in the ears, and blurred vision have occurred.

Central Nervous System

Headache, fatigue, apprehension, confusion.

Miscellaneous

Skin rash, fever, chills, hematuria.

SODIUM EDECRIN (ethacrynic acid) occasionally has caused local irritation and pain after intravenous use.

Read the entire FDA prescribing information for Edecrin (Ethacrynic Acid) »

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Edecrin - User Reviews

Edecrin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Edecrin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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