Effexor XR (Venlafaxine Hydrochloride Extended-Release) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

Effexor XR

Antidepressants: Get the Facts »

What does the new study say about the ineffectiveness of antidepressants?

In findings published in the February issue of the journal PloS Medicine, researchers conclude that when taken as a whole, the data show that only a small group of the most severely depressed patients benefit from taking one of the antidepressants.

For less severely depressed patients, the antidepressants were found to work no better than placebos, leading the researchers to conclude that most patients who take antidepressants probably shouldn't be on them.

Does this study contradict numerous positive studies on antidepressants?

Yes, it does. In a statement, American Psychiatric Association President-elect Nada Stotland, MD, maintains that studies like this one, which compare a single drug to placebo, do not accurately reflect the way doctors prescribe antidepressants today.

Stotland says many people who are depressed do n...

Read the Antidepressants: Get the Facts article »

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Effexor XR

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Effexor XR Patient Information including If I Miss a Dose

What happens if I miss a dose (Effexor XR)?

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Effexor XR)?

Seek emergency medical attention if you think you have taken too much of this medication.

Overdose symptoms may include dizziness, sleepiness, nausea, and numbness or tingling in your hands or feet.

What should I avoid while taking venlafaxine (Effexor XR)?

Avoid drinking alcohol, which can increase some of the side effects of venlafaxine.

Venlafaxine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Tell your doctor if you regularly use other drugs that can cause sleepiness (such as cold or allergy medicine, narcotic pain medication, sedatives, muscle relaxers, or medicines to treat seizures or anxiety). These may add to sleepiness caused by venlafaxine.

What other drugs will affect venlafaxine (Effexor XR)?

Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with venlafaxine may cause you to bruise or bleed easily.

Before taking venlafaxine, tell your doctor if you are using any of the following medicines:

cimetidine (Tagamet, Tagamet HB);
warfarin (Coumadin);
ketoconazole (Nizoral);
tryptophan (sometimes called L-tryptophan);
haloperidol (Haldol) or risperidone (Risperdal);
almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
any other antidepressants such as amitriptyline (Elavil), amoxapine (Ascendin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), or trimipramine (Surmontil).

This list is not complete and there may be other drugs that can interact with venlafaxine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about venlafaxine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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