"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
Patients should be forewarned that the reaction in the treated areas may be unsightly during therapy and, usually, for several weeks following cessation of therapy. Patients should be instructed to avoid exposure to ultraviolet rays during and immediately following treatment with Efudex (fluorouracil) because the intensity of the reaction may be increased. If Efudex (fluorouracil) is applied with the fingers, the hands should be washed immediately afterward. Efudex (fluorouracil) should not be applied on the eyelids or directly into the eyes, nose or mouth because irritation may occur.
Last reviewed on RxList: 5/13/2008
This monograph has been modified to include the generic and brand name in many instances.
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