Brand Names: Eldepryl, Zelapar

Generic Name: selegiline (oral) (Pronunciation: se LE ji leen)

• What is selegiline (Eldepryl)?
• What are the possible side effects of selegiline (Eldepryl)?
• What is the most important information I should know about selegiline (Eldepryl)?
• What should I discuss with my healthcare provider before using selegiline (Eldepryl)?
• How should I take selegiline (Eldepryl)?
• What happens if I miss a dose (Eldepryl)?
• What happens if I overdose (Eldepryl)?
• What should I avoid while using selegiline (Eldepryl)?
• What other drugs will affect selegiline (Eldepryl)?
• Where can I get more information?

What is selegiline (Eldepryl)?

Selegiline prevents the breakdown of a chemical in your brain called dopamine (DO pa meen). Low levels of this chemical are associated with Parkinson's disease.

Selegiline is used together with other medicines to treat symptoms of Parkinson's disease.

Selegiline may also be used for other purposes not listed in this medication guide.

Eldepryl 5 mg-SOM

turquoise, imprinted with Somerser, Eldepryl 5 mg

Selegiline 5 mg tab-APO

round, white, imprinted with A, 3438

What are the possible side effects of selegiline (Eldepryl)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking selegiline and call your doctor at once if you have any of these serious side effects:

• sudden and severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, seizure (convulsions), and sudden numbness or weakness (especially on one side of the body);
• feeling light-headed, fainting;
• hallucinations;
• feeling restless, agitated, or irritable;
• twitching muscle movements; or
• painful or difficult urination.

Less serious side effects may include:

• dizziness, weakness;
• sleep problems (insomnia);
• runny or stuffy nose;
• back pain;
• constipation; or
• mouth sores or ulcers, pain with swallowing (while using Zelapar).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about selegiline (Eldepryl)?

There are many other medicines that can cause serious medical problems if you take them together with selegiline. Tell your doctor about all other prescription and over-the-counter medications you use, including vitamins, minerals, and herbal products.

While taking selegiline, do not drink alcohol or eat foods that are high in tyramine, listed in the "What should I avoid while using selegiline?" section of this leaflet. Eating tyramine while you are using selegiline can raise your blood pressure to dangerous levels and cause life-threatening symptoms.

You should become very familiar with the list of foods to avoid while you are using selegiline.

Do not stop taking selegiline suddenly or you may have harmful side effects. Keep taking the medicine as prescribed. Talk with your doctor before stopping the medication.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking selegiline.