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(epinastine HCl) Ophthalmic Solution
ELESTAT® (epinastine HCl ophthalmic solution) 0.05% is a clear, colorless, sterile isotonic solution containing epinastine HCl, an antihistamine and an inhibitor of histamine release from the mast cell for topical administration to the eyes.
Epinastine HCl is represented by the following structural formula:
C16H15N3HCl Mol. Wt . 285.78
Chemical Name: 3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine hydrochloride
Each mL contains: Active: Epinastine HCl 0.05% (0.5 mg/mL) equivalent to epinastine 0.044% (0.44 mg/mL); Preservative: Benzalkonium chloride 0.01%; Inactives: Edetate disodium; purified water; sodium chloride; sodium phosphate, monobasic; and sodium hydroxide and/or hydrochloric acid (to adjust pH). ELESTAT® has a pH of approximately 7 and an osmolality range of 250 to 310 mOsm/kg.
What are the possible side effects of epinastine ophthalmic (Elestat)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using epinastine ophthalmic and call your doctor at once if you have a serious side effect such as:
- swelling, redness, severe discomfort, crusting or drainage (around your eyelids); or
- severe burning, stinging, or other irritation after using the eye drops.
Less serious side effects may include:
- mild burning, itching, or eye irritation;
What are the precautions when taking epinastine hcl ophthalmic solution (Elestat)?
Before using epinastine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
If you wear contact lenses, consult your doctor about the use of contact lenses when the eyes are red or irritated.
This drug may cause temporary blurred vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with...
Last reviewed on RxList: 1/9/2012
This monograph has been modified to include the generic and brand name in many instances.
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