Elestat (Epinastine HCl Ophthalmic Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Elestat

Allergy »

Allergy facts

Allergy involves an exaggerated response of the immune system.
The immune system is the body's organized defense mechanism against foreign invaders, particularly infections.
Allergens are substances that are foreign to the body and can cause an allergic reaction.
IgE is the allergy antibody.
Allergies can develop at any age.
Your risk of developing allergies is related to your parents' allergy history.

Introduction

In this review you will learn how allergy relates to the immune system. You will begin understanding how and why certain people become allergic. The most common allergic diseases are discussed briefly in this article.

What does an allergy mean?

An allergy refers to an exaggerated reaction by our immune system in response to bodily contact with certain foreign substances. It is exaggerated because these f...

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ELESTAT®
(epinastine HCl) Ophthalmic Solution

DRUG DESCRIPTION

ELESTAT® (epinastine HCl ophthalmic solution) 0.05% is a clear, colorless, sterile isotonic solution containing epinastine HCl, an antihistamine and an inhibitor of histamine release from the mast cell for topical administration to the eyes.

Epinastine HCl is represented by the following structural formula:

ELESTAT® (epinastine HCl) Structural Formula Illustration

C₁₆H₁₅N₃HCl Mol. Wt . 285.78

Chemical Name: 3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine hydrochloride

Each mL contains: Active: Epinastine HCl 0.05% (0.5 mg/mL) equivalent to epinastine 0.044% (0.44 mg/mL); Preservative: Benzalkonium chloride 0.01%; Inactives: Edetate disodium; purified water; sodium chloride; sodium phosphate, monobasic; and sodium hydroxide and/or hydrochloric acid (to adjust pH). ELESTAT® has a pH of approximately 7 and an osmolality range of 250 to 310 mOsm/kg.

What are the possible side effects of epinastine ophthalmic (Elestat)?

Serious side effects are not expected to occur with the use of epinastine ophthalmic.

Commonly, some eye burning, irritation, itching, or redness may occur. Headache and symptoms of a cold have also been reported.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

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What are the precautions when taking epinastine hcl ophthalmic solution (Elestat)?

Before using epinastine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

If you wear contact lenses, consult your doctor about the use of contact lenses when the eyes are red or irritated.

This drug may cause temporary blurred vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with...

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Last reviewed on RxList: 1/9/2012
This monograph has been modified to include the generic and brand name in many instances.