"ANN ARBOR, MI â€” A high rate of patients with atrial fibrillation discontinue warfarin therapy within a year, especially patients who have undergone electrical cardioversion (ECV) or radiofrequency ablation (RFA), according to new research publish"...
In controlled clinical trials, orally administered apixaban in healthy subjects at doses up to 50 mg daily for 3 to 7 days (25 mg twice daily for 7 days or 50 mg once daily for 3 days) had no clinically relevant adverse effects.
In healthy subjects, administration of activated charcoal 2 and 6 hours after ingestion of a 20-mg dose of apixaban reduced mean apixaban AUC by 50% and 27%, respectively. Thus, administration of activated charcoal may be useful in the management of apixaban overdose or accidental ingestion.
ELIQUIS is contraindicated in patients with the following conditions:
Last reviewed on RxList: 9/6/2016
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