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Eliquis

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Eliquis

OVERDOSE

There is no antidote to ELIQUIS. Overdose of ELIQUIS increases the risk of bleeding [see WARNINGS AND PRECAUTIONS].

In controlled clinical trials, orally administered apixaban in healthy subjects at doses up to 50 mg daily for 3 to 7 days (25 mg twice daily for 7 days or 50 mg once daily for 3 days) had no clinically relevant adverse effects.

In healthy subjects, administration of activated charcoal 2 and 6 hours after ingestion of a 20-mg dose of apixaban reduced mean apixaban AUC by 50% and 27%, respectively. Thus, administration of activated charcoal may be useful in the management of apixaban overdose or accidental ingestion.

CONTRAINDICATIONS

ELIQUIS is contraindicated in patients with the following conditions:

Last reviewed on RxList: 4/7/2014
This monograph has been modified to include the generic and brand name in many instances.

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