July 7, 2015
Recommended Topic Related To:

Eliquis

"The U.S. Food and Drug Administration today approved Kcentra (Prothrombin Complex Concentrate, Human) for the urgent reversal of vitamin K antagonist (VKA) anticoagulation in adults with acute major bleeding. Plasma is the only other product appr"...

Eliquis




Overdosage
Contraindications

OVERDOSE

There is no antidote to ELIQUIS. Overdose of ELIQUIS increases the risk of bleeding [see WARNINGS AND PRECAUTIONS].

In controlled clinical trials, orally administered apixaban in healthy subjects at doses up to 50 mg daily for 3 to 7 days (25 mg twice daily for 7 days or 50 mg once daily for 3 days) had no clinically relevant adverse effects.

In healthy subjects, administration of activated charcoal 2 and 6 hours after ingestion of a 20-mg dose of apixaban reduced mean apixaban AUC by 50% and 27%, respectively. Thus, administration of activated charcoal may be useful in the management of apixaban overdose or accidental ingestion.

CONTRAINDICATIONS

ELIQUIS is contraindicated in patients with the following conditions:

Last reviewed on RxList: 4/7/2014
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications

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