August 27, 2016
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Eliquis Patient Information Including Side Effects

Brand Names: Eliquis

Generic Name: apixaban (Pronunciation: a PIX a ban)

What is apixaban (Eliquis)?

Apixaban keeps the platelets in your blood from coagulating (clotting).

Apixaban is used in people with atrial fibrillation (a heart rhythm disorder) to lower the risk of stroke caused by a blood clot.

Apixaban may also be used for purposes not listed in this medication guide.

What are the possible side effects of apixaban (Eliquis)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop;
  • heavy menstrual periods;
  • headache, dizziness, weakness, feeling like you might pass out;
  • red, pink, or brown urine;
  • black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
  • numbness, tingling, or muscle weakness (especially in your legs and feet); or
  • loss of movement in any part of your body.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Eliquis (apixaban tablets) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about apixaban (Eliquis)?

Because apixaban keeps your blood from coagulating (clotting) to prevent unwanted blood clots, this medicine can also make it easier for you to bleed, even from a minor injury such as a fall or a bump on the head. Avoid activities that may increase your risk of bleeding or injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

Call your doctor at once if you have any signs of bleeding such as weakness, feeling like you might pass out, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin, pink or brown urine, bloody or tarry stools, coughing up blood, joint pain or swelling, or heavy menstrual bleeding.

Tell any doctor or dentist who treats you that you are using apixaban. If you need surgery or dental work, you may need to stop using the medicine for a short time.

Some drugs can raise or lower your blood levels of apixaban, which may cause side effects or make apixaban less effective. Many other drugs (including some over-the-counter medicines) can increase your risk of bleeding or life-threatening blood clots. It is very important to tell your doctor about all medicines you have recently used.

Do not stop taking apixaban without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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