"A huge European trial has shown that the 70-gene assay MammaPrint can identify patients with early breast cancer who can safely skip adjuvant chemotherapy, even if they have clinical characteristics suggesting they are at high risk.
Ellence Patient Information Including Side Effects
Brand Names: Ellence
Generic Name: epirubicin (Pronunciation: EP i ROO bi sin)
- What is epirubicin (Ellence)?
- What are the possible side effects of epirubicin (Ellence)?
- What is the most important information I should know about epirubicin (Ellence)?
- What should I discuss with my healthcare provider before I receive epirubicin (Ellence)?
- How is epirubicin given (Ellence)?
- What happens if I miss a dose (Ellence)?
- What happens if I overdose (Ellence)?
- What should I avoid while receiving epirubicin (Ellence)?
- What other drugs will affect epirubicin (Ellence)?
- Where can I get more information?
What is epirubicin (Ellence)?
Epirubicin is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Epirubicin is used to treat breast cancer.
Epirubicin may also be used for purposes not listed in this medication guide.
What are the possible side effects of epirubicin (Ellence)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have:
- pain, burning, irritation, or skin changes where the injection was given;
- feeling short of breath, even with mild exertion;
- swelling, rapid weight gain (especially in your face and midsection);
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- fast, slow, or uneven heartbeats;
- anxiety, sweating, severe shortness of breath, wheezing, gasping for breath;
- chest pain, sudden cough, cough with foamy mucus, rapid breathing, coughing up blood;
- lower back pain, blood in your urine, urinating less than usual or not at all;
- numbness or tingly feeling around your mouth, weak pulse, overactive reflexes, confusion, fainting;
- muscle weakness, tightness, or contraction;
- fever, chills, body aches, flu symptoms, sores in your mouth and throat;
- pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin.
Common side effects may include:
- hot flashes, missed menstrual periods;
- temporary hair loss;
- feeling weak or tired;
- mild nausea, diarrhea; or
- eye redness, puffy eyelids.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Ellence (epirubicin hydrochloride) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about epirubicin (Ellence)?
You should not use this medication if you are allergic to epirubicin or similar medications (Cerubidine, Adriamycin, Idamycin, Novantrone), or if you have an untreated or uncontrolled infection, severe liver disease, severe heart problems, or if you have recently had a heart attack.
Epirubicin can have serious side effects on your heart. Before you are treated with epirubicin, tell your doctor if you have a history of heart disease, heart rhythm disorder, congestive heart failure, or heart attack.
Also tell your doctor about all other medicines you use, especially about any other cancer medications or treatments you have received (including radiation).
Do not use epirubicin if you are pregnant. It could harm the unborn baby.
Epirubicin can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.
Do not receive a "live" vaccine while using epirubicin, or you could develop a serious infection.
Using epirubicin may increase your risk of developing other types of cancer, such as leukemia. Talk with your doctor about your specific risk.
Additional Ellence Information
- Ellence Drug Interactions Center: epirubicin iv
- Ellence Side Effects Center
- Ellence Overview including Precautions
- Ellence FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find support and advances in treatment.