Emadine (Emedastine Difumarate Ophthalmic Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Emadine

Eye Allergy »

Eye allergy facts

Most allergic eye conditions are more irritating than dangerous.
Allergic or vernal keratoconjunctivitis may result in scarring of the cornea and visual problems.
Itchy eyes are probably allergic eyes.
Topical antihistamine/decongestant preparations are effective and safe for mildly itchy, red eyes.
Patanol, a topical mast-cell stabilizer, is a safe, highly effective, long-acting treatment.
Topical steroids should be used with caution and under the supervision of an ophthalmologist.
If in doubt, seek medical advice sooner rather than later.

Eye allergy introduction

The eyes are the windows to the soul because they reflect our state of mind. This certainly can't be true if our eyes are red, swollen, watery, and itchy from an allergic reaction. Severe allergic eye symptoms can be very distressing and are a common reason fo...

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Emadine

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Emadine®
(emedastine difumarate) Ophthalmic Solution 0.05%

DRUG DESCRIPTION

EMADINE ® (emedastine difumarate ophthalmic solution) 0.05% is a sterile ophthalmic solution containing emedastine, a relatively selective, H₁-receptor antagonist for topical administration to the eyes. Emedastine difumarate is a white, crystalline, water-soluble fine powder with a molecular weight of 534.57. The chemical structure is presented below:

Structural Formula:

Chemical Name:

lH-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl), (E)-2-butenedioate (1:2)

Each mL of EMADINE contains: Active: 0.884 mg emedastine difumarate equivalent to 0.5 mg emedastine. Preservative: benzalkonium chloride 0.01%. Inactives: tromethamine; sodium chloride; hydroxypropyl methylcellulose; hydrochloric acid/sodium hydroxide (adjust pH); and purified water. It has a pH of approximately 7.4 and an osmolality of approximately 300 mOsm/kg.

What are the possible side effects of emedastine ophthalmic (Emadine)?

Serious side effects are not expected to occur with the use of emedastine ophthalmic.

Commonly, some eye burning, irritation, itching, dryness, other eye discomfort, or blurred vision may occur. Headache and a bad taste in the mouth have also been reported.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

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What are the precautions when taking emedastine difumarate ophthalmic solution (Emadine)?

Before using emedastine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This drug may cause temporary blurred or unstable vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if this drug passes...

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Last reviewed on RxList: 11/7/2008
This monograph has been modified to include the generic and brand name in many instances.