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"People who suffer chronic pain face a good news/bad news situation in choosing a treatment. There are powerful medicines called opioids that can help manage pain when prescribed for the right condition and when used properly. But when prescribed "...




Embeda Consumer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.




WARNING: See also How to Use section.

This medication is a strong narcotic pain reliever. It should only be used by patients who have been using moderate-to-large amounts of a powerful narcotic medication (such as morphine, oxycodone, fentanyl) regularly. Use of this medication by someone who is not regularly taking narcotic pain relievers can cause serious (possibly fatal) breathing problems (such as very slow and shallow breathing).

This medication should be used only for ongoing pain that requires strong narcotic pain medication at all times for an extended period. It should not be used for quick relief (for use as needed) of sudden, short-term or "breakthrough" pain.

This product is designed to slowly release morphine. Crushing, chewing, or dissolving this medication or using any alcohol may suddenly release a very large (possibly fatal) amount of drug into your body. Do not crush, chew, or dissolve the capsule or the contents of the capsule. Also, do not drink alcohol or use any product that contains alcohol while taking this medication. Check product labels carefully or ask your pharmacist if you are unsure whether a product contains alcohol.

Crushing, chewing, or dissolving the capsule or pellets inside the capsule may cause a sudden large release of naltrexone. This can cause withdrawal symptoms if you have been taking strong narcotics regularly.

Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction).

USES: See also Warning section.

This medication contains morphine in a long-acting form and naltrexone. It is used to treat moderate to severe long-term pain (usually lasting longer than a few days). Morphine is a narcotic pain reliever (opiate-type). It acts on certain centers in the brain to give you pain relief. Naltrexone belongs to a class of drugs known as narcotic antagonists. It is combined with morphine to prevent crushing/dissolving the medication for abuse/misuse.

HOW TO USE: See also Warning section.

Read the Medication Guide provided by your pharmacist before you start taking this product and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth with or without food, usually once or twice daily or as directed by your doctor. Do not take more than 1 dose in 12 hours.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.

Swallow the capsules whole. Do not crush, chew, or dissolve the capsules. Doing so can release all of the drug at once, increasing the risk of side effects.

If you are an adult and have trouble swallowing the capsule, you may open the capsule and carefully sprinkle its contents on a spoonful of soft, cool applesauce just before you take it. Swallow all of the drug/food mixture immediately without chewing. Then rinse your mouth and swallow the rinse liquid to make sure that you have swallowed all of the medicine. Do not chew the mixture or prepare a supply in advance. Do not give this medication through a tube into the stomach (such as a nasogastric tube).

Children should not be given this medication by opening the capsules and sprinkling it on applesauce. There is a risk that a child may chew the drug/food mixture, which can result in a fatal overdose of morphine. See also Warning section and talk to your doctor or pharmacist for more details.

Your doctor may direct you to take quick-acting narcotic or non-narcotic (such as naproxen, ibuprofen) pain medications for sudden (breakthrough) pain. Follow your doctor's or pharmacist's instructions for safely using these medications. If you have been using other long-acting narcotic pain medications or narcotic patches regularly, check with your doctor or pharmacist because you may need to stop using them before you start using this medication. If you are currently using a narcotic patch (such as fentanyl), the effects may continue after it is removed. Ask your doctor or pharmacist when it will be safe to start taking this medication.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, vomiting, diarrhea, watery eyes, muscle aches, runny nose) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.

When this medication is used for a long time, it may not work as well. Your doctor may need to increase your dose or change your medication. Talk with your doctor if this medication stops working well.

Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction. Store this medication in a secure place to prevent theft and keep out of the reach of children.

Tell your doctor if your pain persists or worsens.


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