Recommended Topic Related To:


"People who suffer chronic pain face a good news/bad news situation in choosing a treatment. There are powerful medicines called opioids that can help manage pain when prescribed for the right condition and when used properly. But when prescribed "...


Embeda Patient Information including How Should I Take

What should I discuss with my healthcare provider before using morphine and naltrexone (Embeda)?

You may not be able to take this medicine unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant.

Do not use morphine and naltrexone if you have ever had an allergic reaction to a narcotic medicine. Opioid medicines include codeine (Tylenol #3), hydrocodone (Vicodin), oxycodone (OxyContin, Percocet), propoxyphene (Darvon, Darvocet), morphine (Kadian, MS Contin, Oramorph), and many others.

You should also not take morphine and naltrexone if you are having an asthma attack or if you have a bowel obstruction called paralytic ileus.

Do not use morphine and naltrexone if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use morphine and naltrexone before the MAO inhibitor has cleared from your body.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take morphine and naltrexone:

  • asthma, COPD, sleep apnea, or other breathing disorders;
  • liver or kidney disease;
  • underactive thyroid;
  • curvature of the spine;
  • a history of head injury or brain tumor;
  • gallbladder or pancreas disorders;
  • a blockage in your stomach or intestines;
  • Addison's disease or other adrenal gland disorders;
  • enlarged prostate, urination problems;
  • epilepsy or other seizure disorder;
  • any type of debilitating condition; or
  • mental illness or a history of drug or alcohol addiction.

Morphine and naltrexone may be habit-forming and should be used only by the person it was prescribed for. Morphine and naltrexone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

FDA pregnancy category C. This medication may cause addiction or withdrawal symptoms in a newborn. Before you receive morphine and naltrexone, tell your doctor if you are pregnant. Morphine and naltrexone should not be used during labor and delivery.

Morphine and naltrexone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medicine.

How should I use morphine and naltrexone (Embeda)?

Use this medication exactly as it was prescribed for you. Never take morphine and naltrexone in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Each dose should be spaced at least 12 hours apart.

Do not crush, chew, or dissolve the medicine pellets inside an extended-release capsule. If possible, swallow the pill whole. Crushing or chewing the medicine pellets would cause too much of the drug to be released at one time, which may cause a life-threatening overdose.

To make swallowing easier, you may open the extended-release capsule and sprinkle the medicine into a spoonful of applesauce. Mix only one dose and swallow this mixture right away without chewing. Drink a glass of water to make sure all the medicine has been swallowed. Flush the empty capsule down a toilet.

Do not stop using morphine and naltrexone suddenly. Talk to your doctor about how to avoid withdrawal symptoms.

Store this medication at room temperature, away from heat, moisture, and light. Keep track of how many pills have been used from each new bottle of this medicine. Morphine and naltrexone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

After you have stopped using this medication, flush any unused pills down the toilet. Throw away any unused liquid morphine and naltrexone that is older than 90 days.

Side Effects Centers

Embeda - User Reviews

Embeda User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Embeda sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Chronic Pain/Back Pain

Find tips and advances in treatment.