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Nausea and vomiting facts

  • Nausea and vomiting are symptoms of a disease or condition. The underlying cause of the illness causing nausea and vomiting should be identified and treated.
  • Nausea and vomiting symptom control is important both for comfort's sake and to prevent dehydration.
  • Dehydration can worsen nausea and vomiting.
  • Medication may be available to control symptoms of nausea and vomiting.

Introduction to nausea and vomiting

Nausea and vomiting are symptoms of an underlying illness and not a specific disease. Nausea is the sensation that the stomach wants to empty itself, while vomiting (emesis) or throwing up, is the act of forcible emptying of the stomach. The term "dry heaves" refers to an episode of vomiting where there is no food in the stomach to vomit, and only clear secretions are vomited.

Vomiting is a violent act in which the stomach almost...

Emend Capsules

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Emend Capsules Patient Information including If I Miss a Dose

What happens if I miss a dose (Emend Capsules)?

Call your doctor for instructions if you forget to take your medicine within the prescribed length of time before your chemotherapy or surgery.

What happens if I overdose (Emend Capsules)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness and headache.

What should I avoid while taking aprepitant (Emend Capsules)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using aprepitant.

What other drugs will affect aprepitant (Emend Capsules)?

Aprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with aprepitant and for at least 1 month after your treatment ends.

Before taking aprepitant, tell your doctor if you are using any of the following drugs:

  • diltiazem (Cardizem, Cartia, Tiazac);
  • tolbutamide (Orinase);
  • a blood thinner such as warfarin (Coumadin);
  • midazolam (Versed) or similar medicines such as Valium, Xanax, or Tranxene;
  • an antidepressant such as nefazodone (Serzone) or paroxetine (Paxil);
  • an antibiotic such as clarithromycin (Biaxin) or rifampin (Rifater, Rifamate);
  • an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
  • certain cancer medicines such as docetaxel (Taxotere), etoposide (VePesid), irinotecan (Camptosar), ifosfamide (Ifex), imatinib (Gleevec), paclitaxel (Onxol, Taxol), vinblastine (Velban), or vincristine (Oncovin, Vincasar);
  • HIV medicines such as nelfinavir (Viracept), lopinavir/ritonavir (Kaletra), or ritonavir (Norvir);
  • seizure medication such as carbamazepine (Tegretol, Carbatrol) or phenytoin (Dilantin); or
  • steroid medicine such as dexamethasone (Decadron, Hexadrol) or methylprednisolone (Medapred, Solu-Medrol).

This list is not complete and there may be other drugs that can interact with aprepitant. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about aprepitant.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2010 Cerner Multum, Inc. Version: 2.1. Revision date: 08/03/2009.

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