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In this Article

• What is fosaprepitant (Emend Injection)?
• What are the possible side effects of fosaprepitant (Emend Injection)?
• What is the most important information I should know about fosaprepitant (Emend Injection)?
• What should I discuss with my health care provider before I receive fosaprepitant (Emend Injection)?
• How is fosaprepitant given (Emend Injection)?
• What happens if I miss a dose (Emend Injection)?
• What happens if I overdose (Emend Injection)?
• What should I avoid while receiving fosaprepitant (Emend Injection)?
• What other drugs will affect fosaprepitant (Emend Injection)?
• Where can I get more information?

What happens if I miss a dose (Emend Injection)?

Since fosaprepitant injection is given only once on the first day of your chemotherapy treatment, you are not likely to be on a dosing schedule.

What happens if I overdose (Emend Injection)?

An overdose of this medication is not likely to occur since it is given by a healthcare professional. However, overdose symptoms may include drowsiness and headache.

What should I avoid while receiving fosaprepitant (Emend Injection)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are being treated with fosaprepitant.

What other drugs will affect fosaprepitant (Emend Injection)?

Fosaprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with fosaprepitant and for at least 1 month after your treatment ends.

Before taking fosaprepitant, tell your doctor if you are using any of the following drugs:

• diltiazem (Cardizem, Cartia, Tiazac);
• tolbutamide (Orinase);
• a blood thinner such as warfarin (Coumadin);
• midazolam (Versed) or similar medicines such as Valium, Xanax, or Tranxene;
• an antidepressant such as nefazodone (Serzone) or paroxetine (Paxil);
• an antibiotic such as clarithromycin (Biaxin) or rifampin (Rifater, Rifamate);
• an antifungal medication such as itraconazole (Sporanox), or ketoconazole (Nizoral);
• certain cancer medicines such as etoposide (VePesid), irinotecan (Camptosar), ifosfamide (Ifex), imatinib (Gleevec), paclitaxel (Onxol, Taxol), vinblastine (Velban), or vincristine (Oncovin, Vincasar);
• HIV medicines such as nelfinavir (Viracept), lopinavir/ritonavir (Kaletra), or ritonavir (Norvir);
• seizure medication such as carbamazepine (Tegretol, Carbatrol) or phenytoin (Dilantin); or
• steroid medicine such as dexamethasone (Decadron, Hexadrol) or methylprednisolone (Medapred, Solu-Medrol).

This list is not complete and there may be other drugs that can interact with fosaprepitant. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about fosaprepitant.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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