July 27, 2016
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Empirin Codeine

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Empirin Codeine


Aspirin and Codeine
(acetylsalicylic acid and codeine)

(WARNING: May be habit forming)

Aspirin (acetylsalicylic acid) occurs as white crystals, commonly tabular or needle-like, or white, crystalline powder. It is odorless or has a faint odor. Its chemical name is: 2-(acetyloxy)benzoic acid. Its molecular formula is:

    C9H8O4 with a molecular weight of 180.16

Codeine is an alkaloid, obtained from opium or prepared from morphine by methylation. Codeine phosphate occurs as fine, white, needle-shaped crystals, or white, crystalline powder. It is odorless and is affected by light. Its chemical name is: 7,8-didehydro-4,5oe epoxy-3-methoxy-17~ methylmorphinan~6oe-ol phosphate (1 :1) (salt) hemihydrate. Its molecular formula is:

    C18H21NO3†H3PO4†1/2 H2O with a molecular weight of 406.37

Aspirin and codeine phosphate tablets for oral administration combine the following inactive ingredients: colloidal silicon dioxide, corn starch, microcrystalline cellulose, povidone, and stearic acid.

What are the possible side effects of aspirin and codeine (Empirin with Codeine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; runny nose, wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek emergency medical attention if a child taking this medication has any of the following life-threatening side effects: noisy breathing, sighing, slow breathing with long pauses between breaths; being unusually sleepy or hard to wake up; blue colored lips.

Call your doctor at once if you have a serious side effect such as:

  • severe stomach pain or...

Read All Potential Side Effects and See Pictures of Empirin Codeine »

What are the precautions when taking aspirin and codeine (Empirin Codeine)?

Consult your...

Read All Potential Precautions of Empirin Codeine »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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