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Enbrel Drug Center

Enbrel (etanercept) is a tumor necrosis factor inhibitor used to treat certain autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, and plaque psoriasis. There is no generic Enbrel available currently. Side effects of Enbrel include nausea, vomiting, headache, redness or discomfort at the injection site, heartburn, cough, and weakness.

Enbrel is available in three preparations; 0.98 mL of a 50 mg/mL solution of etanercept, 0.51 mL of a 50 mg/mL solution of etanercept and 25 mg etanercept. All are used for injection; only the 25 mg strength is available in a multiuse vial, the others are available in a prefilled syringe. Starting dose is often 50 mg injected twice a week in adults and 0.8 mg per Kg in pediatric patients weighing less than 63 Kg. Other doses may be used. Serious side effects of Enbrel may include seizures, bruising or bleeding, skin changes (rash, pustules or blistering skin), swelling and difficult breathing or swallowing, vision changes, paresthesias, weakness, and dizziness. Warnings are given for Enbrel use; Enbrel users are at increased risk for developing serious infections that may lead to hospitalization or death and for the development of lymphoma and other malignancies and death in children and adolescent patients treated with TNF blockers, including Enbrel. Patients receiving cyclophosphamide therapy are not recommended to use Enbrel and patients should not obtain any live vaccine while taking Enbrel. There are no studies available on Enbrel use in pregnant or breastfeeding women or their infants.

Our Enbrel Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.