"Consumers and health care professionals will soon find updated labeling for extended-release and long-acting opioid pain relievers to help ensure their safe and appropriate use.
In addition to requiring new labeling on these prescript"...
- Clinician Information:
Endocet Patient Information including How Should I Take
In this Article
- What is acetaminophen and oxycodone (Endocet)?
- What are the possible side effects of acetaminophen and oxycodone?
- What is the most important information I should know about acetaminophen and oxycodone?
- What should I discuss with my healthcare provider before taking acetaminophen and oxycodone?
- How should I take acetaminophen and oxycodone?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking acetaminophen and oxycodone?
- What other drugs will affect acetaminophen and oxycodone?
- Where can I get more information?
What should I discuss with my healthcare provider before taking acetaminophen and oxycodone?
Do not use this medication if you are allergic to acetaminophen (Tylenol) or oxycodone.
Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take medicine that contains acetaminophen.
To make sure you can safely take acetaminophen and oxycodone, tell your doctor if you have any of these other conditions:
- asthma, COPD, sleep apnea, or other breathing disorders;
- liver or kidney disease;
- a history of head injury or brain tumor;
- epilepsy or other seizure disorder;
- low blood pressure;
- a stomach, intestinal, or pancreas disorder;
- underactive thyroid;
- Addison's disease or other adrenal gland disorder;
- enlarged prostate, urination problems;
- curvature of the spine;
- mental illness; or
- a history of drug or alcohol addiction.
Oxycodone may be habit forming and should be used only by the person it was prescribed for. Never share acetaminophen and oxycodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby, but it could cause breathing problems or addiction/withdrawal symptoms in a newborn. Before you take acetaminophen and oxycodone, tell your doctor if you are pregnant or plan to become pregnant during treatment.
Acetaminophen and oxycodone may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take acetaminophen and oxycodone?
Take exactly as prescribed. Never take acetaminophen and oxycodone in larger amounts, or for longer than recommended by your doctor. An overdose of acetaminophen can damage your liver or cause death. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
One acetaminophen and oxycodone tablet may contain up to 650 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.
Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking acetaminophen and oxycodone. Do not use a stool softener (laxative) without first asking your doctor.
Do not stop using this medicine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using acetaminophen and oxycodone.
Acetaminophen can cause false results with certain lab tests for glucose (sugar) in the urine. Talk to your doctor if you are diabetic and you notice changes in your glucose levels during treatment.
If you need surgery, tell the surgeon ahead of time that you are using acetaminophen and oxycodone. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture and heat.
After you have stopped using this medication, flush any unused pills down the toilet.
Keep track of the amount of medicine used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Additional Endocet Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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