Enlarged Spleen (Splenomegaly) (cont.)

Depending upon the cause, the enlarged spleen may return to normal size and function when the underlying disease is treated or resolved.

• Commonly, in infectious mononucleosis, the spleen returns to normal as the infection gets better.
  
  
• In some circumstances, removing the spleen is part of the treatment and can make the person much more susceptible to infections.
  
  
• Many illnesses and diseases result with the enlarged spleen as a permanent physical finding and may result in only a fair prognosis because the person may be more prone to splenic injury, infections, and abnormal bleeding.

• The spleen is responsible for filtering the blood and removing aged and damaged cells. It is also a key part of the immune and lymph system of the body.
  
  
• An enlarged spleen is not normal and usually is a physical finding of an underlying disease or illness.
  
  
• Blood tests may be used to help make the diagnosis of underlying diseases that are associated with splenomegaly.
  
  
• Ultrasound, CT, and MRI can help measure the size of the spleen and also look for associated abnormalities in the abdominal cavity.
  
  
• The treatment for an enlarged spleen is directed to the underlying illness. Splenectomy (removal of the spleen) may be part of that treatment.

REFERENCES: eMedicine.com; "Splenomegaly."

Harrison's Principles of Internal Medicine. Braumwald E, Fauci AS, et al. 17th Edition. 2007. McGraw Hill.

Last Editorial Review: 12/9/2009 10:25:07 AM

Source: MedicineNet.com
http://www.medicinenet.com/enlarged_spleen_splenomegaly/article.htm