"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.
(Generic versions may still be available.)
Enlon Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Enlon (edrophonium injection) is a short and rapid-acting cholinergic drug used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures. The brand name Enlon is discontinued, but generic versions may be available. Common side effects of Enlon (edrophonium injection) include watery eyes, vision problems, changes in your voice, nausea, vomiting, diarrhea, stomach pain, weakness, or muscle twitching.
The intravenous dosage of Enlon for adults: A tuberculin syringe containing 1 mL (10 mg) of Enlon is prepared with an intravenous needle, and 0.2 mL (2 mg) is injected intravenously within 15 to 30 seconds. The needle is left in situ. Only if no reaction occurs after 45 seconds is the remaining 0.8 mL (8 mg) injected. Enlon may interact with other drugs. Tell your doctor all medications and supplements you use. Enlon may be harmful to a fetus. Tell your doctor if you are pregnant before you receive this medication. Consult your doctor before breastfeeding.
Our Enlon (edrophonium injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Enlon in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
- slow heart rate;
- chest pain, weak pulse, increased sweating, and dizziness;
- feeling like you might pass out;
- weak or shallow breathing;
- urinating more than usual;
- seizures (convulsions); or
- trouble swallowing.
Less serious side effects (some of which can be expected as part of a positive test reaction) may include:
- watery eyes, vision problems;
- changes in your voice;
- mild nausea, vomiting, diarrhea, stomach pain;
- weakness; or
- muscle twitching.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Enlon (Edrophonium Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Enlon FDA Prescribing Information: Side Effects
Careful observation should be made for severe cholinergic reactions in the hyperreactive individual. The myasthenic patient in crisis who is being tested with Enlon (edrophonium injection) ® should be observed for bradycardia or cardiac standstill and cholinergic reactions if an overdose is given.
The following reactions common to anticholinesterase agents may occur, although not all of these reactions have been reported with the administration of Enlon (edrophonium injection) ®, probably because of its short duration of action and limited indications:
|CNS:||Convulsions, dysarthria, dysphonia, dysphagia.|
Arrhythmias (especially bradycardia), fall in cardiac output leading to hypotension. Increased salivary, gastric and intestinal secretion, nausea, vomiting, increased peristalsis, diarrhea, abdominal cramps.
|Skeletal Muscle:||Weakness, fasciculations.|
|Miscellaneous:||Increased urinary frequency and incontinence, diaphoresis.|
Read the entire FDA prescribing information for Enlon (Edrophonium Injection)
Additional Enlon Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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