May 23, 2017

Entereg Capsules

Entereg Capsules Patient Information including How Should I Take

What should I discuss with my health care provider before I receive alvimopan (Entereg Capsules)?

You should not use this medication if you are allergic to alvimopan, if you have severe liver or kidney disease, or if you have used a narcotic medication within the past 7 days, such as:

  • codeine (Tylenol #3, Cheratuss, Guaiatuss);
  • fentanyl (Abstral, Actiq, Fentora, Duragesic, Ionsys, Lazanda, Onsolis);
  • hydrocodone (Lortab, Vicodin, Vicoprofen);
  • hydromorphone (Dilaudid, Palladone);
  • levorphanol (Levo-Dromoran);
  • meperidine (Demerol);
  • methadone (Methadose, Diskets, Dolophine);
  • morphine (Avinza, Kadian, MS Contin, Oramorph);
  • nalbuphine (Nubain);
  • oxycodone (OxyContin, Combunox, Roxicodone, Percocet);
  • oxymorphone (Numorphan, Opana); or
  • pentazocine (Talwin).

To make sure you can safely take alvimopan, tell your doctor if you have any of these other conditions:

  • liver disease; or
  • kidney disease.

FDA pregnancy category B. Alvimopan is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether alvimopan passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is alvimopan given (Entereg Capsules)?

Alvimopan is given only in a hospital for a short period of time.

You will receive your first dose of alvimopan up to 5 hours before your surgery. You will then be given additional doses two times per day for up to 7 days.

Side Effects Centers

Additional Entereg Capsules Information

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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