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Entex La

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Entex La

Entex La

Entex La Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Entex LA (phenylephrine hydrochloride and guaifenesin) is used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu. Phenylephrine is a decongestant, and guaifenesin is an expectorant. This medication is available in generic form. Common side effects include nausea, vomiting, upset stomach, loss of appetite, warmth, tingling, or redness under the skin, feeling excited or restless, insomnia, skin rash, itching, headache, or dizziness.

The dose of Entex LA for adults and children 12 years of age and older is one tablet twice daily (every 12 hours). The pediatric dose for children 6 to 12 years is 1/2 tablet twice daily (every 12 hours). Entex LA may interact with medicines to treat high blood pressure, beta-blockers, or antidepressants. Tell your doctor all medications you use. During pregnancy, Entex LA should be used only if prescribed. This medication passes into breast milk and could harm a nursing baby. Consult your doctor before breast-feeding.

Our Entex LA (phenylephrine hydrochloride and guaifenesin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Entex La in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure); or
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • vomiting, upset stomach;
  • warmth, tingling, or redness under your skin;
  • feeling excited or restless (especially in children);
  • sleep problems (insomnia);
  • skin rash or itching;
  • headache; or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Entex La (Guaifenesin and Phenylephrine) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Entex La FDA Prescribing Information: Side Effects
(Adverse Reactions)


Possible adverse reactions include nervousness, insomnia, restlessness, headache, nausea, or gastric irritation. These reactions seldom, if ever, require discontinuation of therapy. Urinary retention may occur in patients with prostatic hypertrophy.

Side effects may include:
Anxiety, convulsions, depression, difficulty breathing, difficulty urinating (in men with an enlarged prostate), hallucinations, headache, inability to sleep or difficulty sleeping, increased heart beat, irritability, irritated stomach, nausea, nervousness, paleness, palpitations, restlessness, tremor, weakness, vomiting

Read the entire FDA prescribing information for Entex La (Guaifenesin and Phenylephrine) »


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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