Eovist (Gadoxetate Disodium Injection) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

Eovist

Liver Disease »

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

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Eovist

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Eovist Patient Information including How Should I Take

What should I discuss with my health care provider before receiving gadoxetate (Eovist)?

Gadoxetate can cause a life-threatening condition in people with advanced kidney disease who are undergoing an MRI. The symptoms of this condition include:

burning, itching, swelling, and tightening or hardening of your skin;
muscle weakness;
pain or stiffness in your arms, hands, legs, or feet;
deep bone pain in your ribs or your hips;
yellow patches on the whites of your eyes; or
skin redness or discoloration.

Before receiving this medication, tell your doctor if you have kidney disease. You may not be able to receive an MRI with gadoxetate.

If you have certain other conditions, you may not be able to receive gadoxetate, or you may need a dose adjustment or special tests during treatment. Before receiving gadoxetate, tell your doctor if you have ever had any type of reaction to another contrast agent, or if you have:

liver disease;
a bleeding or blood-clotting disorder;
a history of stroke, blood clots, or circulation problems;
asthma, hay fever, or a history of food or drug allergies;
if you have had a liver transplant; or
if you are on dialysis.

FDA pregnancy category C. It is not known whether gadoxetate is harmful to an unborn baby. Before you receive this medication, tell your doctor if you are pregnant.

It is not known whether gadoxetate passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is gadoxetate used (Eovist)?

Gadoxetate is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting during your MRI.

Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.

Gadoxetate can cause you to have unusual results with certain medical tests for at least 24 hours after your MRI. Tell any doctor who treats you that you have received gadoxetate

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