Eovist (Gadoxetate Disodium Injection) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Eovist

Liver Disease »

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

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Eovist

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Eovist Patient Information Including Side Effects

Brand Names: Eovist

Generic Name: gadoxetate (Pronunciation: gad OX e tate)

What is gadoxetate (Eovist)?

Gadoxetate is a contrast agent. Gadoxetate produces magnetic effects. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

Gadoxetate is used to help diagnose certain disorders of the liver.

Gadoxetate may also be used for other not those listed in this medication guide.

What are the possible side effects of gadoxetate (Eovist)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some of the side effects of gadoxetate can occur up to several days after you have received the medication.

Call your doctor at once if you have any of these serious side effects:

trouble breathing;
chest pain;
fast or pounding heartbeats; or
skin changes where the injection was given.

Less serious side effects may include:

headache, tired feeling;
dizziness, spinning sensation;
nausea, vomiting;
back pain;
dry mouth, mouth pain or discomfort;
decreased sense of taste or smell;
increased sweating or salivation;
warmth, redness, or tingly feeling under your skin;
mild skin rash or itching;
feeling unusually hot; or
cold feeling, warmth, pain, or burning where the injection was given.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about gadoxetate (Eovist)?

Gadoxetate can cause a life-threatening condition in people with advanced kidney disease who are undergoing an MRI. The symptoms of this condition include:

burning, itching, swelling, and tightening or hardening of your skin;
muscle weakness;
pain or stiffness in your arms, hands, legs, or feet;
deep bone pain in your ribs or your hips;
yellow patches on the whites of your eyes; or
skin redness or discoloration.

Before receiving this medication, tell your doctor if you have kidney disease. You may not be able to receive an MRI with gadoxetate.

Also tell your doctor if you have liver disease, a bleeding or blood-clotting disorder, a history of stroke or blood clots, circulation problems, asthma or allergies, if you have had a liver transplant, or if you are on dialysis.

Some of the side effects of gadoxetate can occur up to several days after you have received the medication.

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