April 30, 2016
Recommended Topic Related To:

Epaned

"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...

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Epaned

Overdosage
Contraindications

OVERDOSE

Limited data are available in regard to overdosage in humans.

Single oral doses of enalapril above 1,000 mg/kg and ≥ 1,775 mg/kg were associated with lethality in mice and rats, respectively.

The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of normal saline solution.

Enalaprilat may be removed from general circulation by hemodialysis and has been removed from neonatal circulation by peritoneal dialysis.

CONTRAINDICATIONS

EPANED is contraindicated in patients with:

Do not co-administer aliskiren with EPANED in patients with diabetes [see DRUG INTERACTIONS].

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 1/6/2016

Overdosage
Contraindications

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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