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Ephedrine

What is narcolepsy?

Narcolepsy is a chronic disease of the central nervous system. Excessive daytime sleepiness (EDS) is the main symptom and is present in 100% of patients with narcolepsy. Other primary symptoms of narcolepsy include:

  • loss of muscle tone (cataplexy),
  • distorted perceptions (hypnagogic hallucinations), and
  • inability to move or talk (sleep paralysis).

Additional symptoms include disturbed nocturnal sleep and automatic behavior (patients carry out certain actions without conscious awareness). All of the symptoms of narcolepsy may be present in various combinations and degrees of severity.

Narcolepsy usually begins in teenagers or young adults and affects both sexes equally. The first symptom to appear is excessive daytime sleepiness, which may remain unrecognized for a long time in that it develops gradually over time. The other symptoms can follow excessive daytime sleepiness by months...

Ephedrine

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Ephedrine Sulfate
Injection, USP

For IM, IV or SC Use 50 mg/mL pH 4.5 - 7.0

DRUG DESCRIPTION

Ephedrine Sulfate Injection, USP is a sterile solution of 50 mg ephedrine sulfate in water for injection.

Ephedrine occurs as fine, white, odorless crystals or powder and darkens on exposure to light. It is freely soluble in water and sparingly soluble in alcohol.

The chemical name for ephedrine sulfate is (C10H15NO)2•H2SO4 benzenemethanol α - [1 - (methylamino) ethyl] - sulfate (2:1) (salt). Its molecular weight is 428.54.

The structural formula is:

EPHEDRINE SULFATE Structural Formula Illustration

Last reviewed on RxList: 3/30/2009
This monograph has been modified to include the generic and brand name in many instances.

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