April 29, 2017
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Epinastine Hydrochloride

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Epinastine Hydrochloride Ophthalmic Solution

epinastine hydrochloride


Epinastine HCl Ophthalmic Solution 0.05% is a clear, colorless, sterile isotonic solution containing epinastine HCl, an antihistamine and an inhibitor of histamine release from the mast cell for topical administration to the eyes.

Epinastine HCl is represented by the following structural formula:

EPINASTINE HYDROCHLORIDE- epinastine hydrochloride Structural Formula Illustration

C16H15N3HCl       Mol. Wt. 285.78

Chemical Name

3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo [1,5-a]azepine hydrochloride

Each mL Contains

Active: epinastine HCl 0.05% (0.5 mg/mL) equivalent to epinastine 0.044% (0.44 mg/mL); Preservative: benzalkonium chloride 0.01%; Inactives: edetate disodium; water for injection; sodium chloride; sodium phosphate, monobasic; and sodium hydroxide and/or hydrochloric acid (to adjust pH). Epinastine HCl has a pH of approximately 7 and an osmolality range of 250 to 310 mOsm/kg.

Last reviewed on RxList: 1/13/2017
This monograph has been modified to include the generic and brand name in many instances.

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