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Impetigo (pronounced im-puh-TIE-go) is a contagious, superficial infection of the skin caused by staphylococcus (Staph) and streptococcus (Strep) bacteria. Impetigo is more common in children (especially 2- to 5-year-olds) than in adults. Impetigo is most likely to occur in warm and humid environments and is most commonly spread by close contact (such as family members).
There are two kinds of impetigo:
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ERYC®
(Erythromycin) Delayed-Release Capsules, USP
To reduce the development of drug-resistant bacteria and maintain the effectiveness of ERYC® and other antibacterial drugs, ERYC should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration. Each ERYC capsule contains 250 mg of erythromycin base. Also contains: lactose NF, povidone USP, FD&C Yellow #6 and other ingredients. The capsule shell contains gelatin NF, titanium dioxide USP, FD&C Yellow #6.
Erythromycin is produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids but it is the base which is microbiologically active. Erythromycin base is (3R *, 4S *, 5S *, 6R *, 7R *, 9R *, 11R *, 12R *, 13S *, 14R *)-4[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6- trideoxy-3-(dimethylamino)-β-D-xylohexopyranosyl]oxy]-oxacyclo-tetradecane-2,10-dione.
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Last reviewed on RxList: 2/24/2012
This monograph has been modified to include the generic and brand name in many instances.
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