Erygel Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Erygel (erythromycin topical) Gel USP 2% is a topical (for the skin) antibiotic used to treat bacterial infections such as severe acne. This medication is available in generic form. Common side effects include burning, redness, itching, or dry/peeling/oily skin, especially in the first few days as your body adjusts to the medication. Eye irritation may also occur.
Erygel Topical Gel should be applied sparingly as a thin film dose to affected area(s) once or twice a day after the skin is thoroughly cleansed and patted dry. Spread the medication lightly rather than rubbing it in. Erygel may interact with other drugs. Avoid using other medications on the areas you treat with Erygel unless instructed by your doctor. Avoid using skin products that can cause irritation, such as harsh soaps or skin cleansers, or skin products with alcohol, spices, astringents, or lime. Tell your doctor all medications and supplements you use. During pregnancy, Erygel should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Erygel (erythromycin topical) Gel USP 2% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Erygel in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using erythromycin topical and call your doctor at once if you have any of these serious side effects:
- severe burning, stinging, or redness;
- oozing or other signs of skin infection;
- worsening of your skin condition; or
- diarrhea that is watery or bloody.
Less serious side effects may include:
- mild skin irritation or tenderness;
- dry or oily skin;
- peeling; or
- mild eye irritation.
Read the entire detailed patient monograph for Erygel (Erythromycin Topical Gel) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Erygel Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Rarely, use of this medication may result in other types of skin infections (fungal or other bacterial infections). Contact your doctor if you notice any unusual skin irritation or other symptoms.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Erygel (Erythromycin Topical Gel)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Erygel FDA Prescribing Information: Side Effects
In controlled clinical trials, the incidence of burning associated with ERYGEL® (erythromycin topical gel) Topical Gel was approximately 25%. The following additional local adverse reactions have been reported occasionally: peeling, dryness, itching, erythema, and oiliness. Irritation of the eyes and tenderness of the skin have also been reported with the topical use of erythromycin. Ageneralized urticarial reaction, possibly related to the use of erythromycin, which required systemic steroid therapy has been reported.
Read the entire FDA prescribing information for Erygel (Erythromycin Topical Gel) »
Additional Erygel Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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