Diphtheria is an infectious disease caused by the bacterium Corynebacterium diphtheriae. This disease primarily affects the mucous membranes of the respiratory tract (respiratory diphtheria), although it may also affect the skin (cutaneous diphtheria) and lining tissues in the ear, eye, and the genital areas.
Throughout history, diphtheria was a leading cause of death among children, and it was once referred to as the "strangling angel of children." Through the ages, several epidemics struck Europe, and even the American colonies were affected by an outbreak in the 18th century. Most recently, in the 1990s, large outbreaks of diphtheria occurred in Russia and in the former independent states of the Soviet Union.
The diphtheria bacterium was first identified in the 1880s. In the 1890s, the antitoxin against diphtheria was developed, with the first vacc...
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Eryped 200
(erythromycin ethylsuccinate) Suspension
Eryped 400
(erythromycin ethylsuccinate) Suspension
Eryped Drops
(erythromycin ethylsuccinate) Suspension
To reduce the development of drug-resistant bacteria and maintain the effectiveness of EryPed (erythromycin ethylsuccinate) and other antibacterial drugs, EryPed (erythromycin ethylsuccinate) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Erythromycin is produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids. The base, the stearate salt, and the esters are poorly soluble in water. Erythromycin ethylsuccinate is an ester of erythromycin suitable for oral administration. Erythromycin ethylsuccinate is known chemically as erythromycin 2'-(ethyl succinate). The molecular formula is C43H75NO16 and the molecular weight is 862.06. The structural formula is:
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EryPed 200 and EryPed Drops (erythromycin ethylsuccinate for oral suspension) when reconstituted with water, forms a suspension containing erythromycin ethylsuccinate equivalent to 200 mg erythromycin per 5 mL (teaspoonful) or 100 mg per 2.5 mL (dropperful) with an appealing fruit flavor. EryPed (erythromycin ethylsuccinate) 400 when reconstituted with water, forms a suspension containing erythromycin ethylsuccinate equivalent to 400 mg of erythromycin per 5 mL (teaspoonful) with an appealing banana flavor.
These products are intended primarily for pediatric use but can also be used in adults.
EryPed 200 (erythromycin ethylsuccinate) , EryPed (erythromycin ethylsuccinate) 400 and EryPed (erythromycin ethylsuccinate) Drops
Caramel, polysorbate, sodium citrate, sucrose, xanthan gum and artificial flavors.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Less serious side effects may...
Read All Potential Side Effects and See Pictures of EryPed »
Before taking erythromycin, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (e.g., azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, a certain type of muscle disease (myasthenia gravis).
Erythromycin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require immediate medical...
Last reviewed on RxList: 3/18/2011
This monograph has been modified to include the generic and brand name in many instances.
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