Erythrocin Lactobionate (Erythromycin Lactobionate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Erythrocin Lactobionate

Endocarditis »

What is endocarditis?

Endocarditis is a serious infection of one of the four heart valves.

What causes endocarditis?

Endocarditis is caused by a growth of bacteria on one of the heart valves, leading to an infected mass called a "vegetation". The infection may be introduced during brief periods of having bacteria in the bloodstream, such as after dental work, colonoscopy, and other similar procedures.

What are the symptoms of endocarditis?

Patients with endocarditis can develop:

fever,
fatigue,
chills,
weakness
aching joints and muscles,
night sweats,
edema (fluid collection) in the leg(s), foot (feet), and abdomen,
malaise,
shortness of breath, and
occasionally, scattered small skin lesions.

In endocarditis, blood cultures can often detect the bacteria causing the endoca...

Read the Endocarditis article »

Erythrocin Lactobionate

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ERYTHROCIN® LACTOBIONATE - I.V.
Sterile Erythromycin Lactobionate, USP

For I.V. use only

To reduce the development of drug-resistant bacteria and maintain the effectiveness of erythromycin and other antibacterial drugs, erythromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

Erythromycin is produced by a strain of Streptomyces erythraeus and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids.

Erythrocin Lactobionate (Sterile Erythromycin Lactobionate, USP), is a soluble salt of erythromycin suitable for intravenous administration. It is available as a sterile, lyophilized powder in vials containing the equivalent of 500 mg or 1 g of erythromycin activity. It is prepared as a solution and lyophilized in its final container.

Erythromycin lactobionate is chemically known as erythromycin mono (4-0-β-Dgalactopyranosyl-D-gluconate) (salt). The structural formula is: