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Erythrocin Stearate

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Erythrocin Stearate

ERYTHROCIN® STEARATE
(erythromycin stearate) Tablets, USP
Filmtab® Tablets

To reduce the development of drug-resistant bacteria and maintain the effectiveness of ERYTHROCIN STEARATE (erythromycin stearate tablets) Filmtab tablets and other antibacterial drugs, ERYTHROCIN STEARATE Filmtab tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

ERYTHROCIN STEARATE Filmtab tablets (erythromycin stearate tablets, USP) are an antibacterial product containing the stearate salt of erythromycin in a unique film coating.

Erythromycin is produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids. Erythromycin is a white to off-white powder, slightly soluble in water, and soluble in alcohol, chloroform, and ether. Erythromycin stearate is known chemically as erythromycin octadecanoate. The molecular formula of erythromycin stearate is C37H67NO13•C18H36O2, and the molecular weight is 1018.43. The structural formula is:

ERYTHROCIN®  erythromycin stearate tablets, USP)  Structural Formula Illustration

Inactive Ingredients

250 mg tablet: Cellulosic polymers, corn starch, D&C Red No. 7, polacrilin potassium, polyethylene glycol, povidone, propylene glycol, sodium carboxymethylcellulose, sodium citrate, sorbic acid, sorbitan monooleate and titanium dioxide. 500 mg tablet: Cellulosic polymers, corn starch, FD&C Red No. 3, magnesium hydroxide, polacrilin potassium, povidone, propylene glycol, sorbitan monooleate, titanium dioxide and vanillin.

What are the precautions when taking erythromycin stearate tablets (Erythrocin Stearate)?

Before taking erythromycin, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (such as azithromycin, clarithromycin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, a certain type of muscle disease (myasthenia gravis).

Erythromycin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention...

Read All Potential Precautions of Erythrocin Stearate »

Last reviewed on RxList: 9/10/2008
This monograph has been modified to include the generic and brand name in many instances.

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