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Erythromycin Ethylsuccinate

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Erythromycin Ethylsuccinate Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

E.E.S. (erythromycin ethylsuccinate) is used to treat many different types of infections caused by bacteria. It is in a group of drugs called macrolide antibiotics. This medication is available in generic form. Common side effects include nausea, vomiting, abdominal pain, diarrhea, dizziness, headache, feeling tired, vaginal itching or discharge, or mild itching or skin rash.

The usual adult dose of erythromycin ethylsuccinate is 400 mg every 6 hours. Dosage may be increased up to 4 g per day according to the severity of the infection. The pediatric dose in mild to moderate infections is 30 to 50 mg/kg/day in equally divided doses every 6 hours. Erythromycin ethylsuccinate may interact with bromocriptine, cilostazol, cyclosporinem, digoxin, disopyramide, quinidine, sildenafil, tacrolimus, theophylline, verapamil, vinblastine, alprazolam or triazolam, blood thinners, carbamazepine, phenytoin, valproic acid, cholesterol-lowering medication, ergotamine, dihydroergotamine, or other antibiotics. Tell your doctor all medications you are taking. Erythromycin ethylsuccinate is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication can pass into breast milk and may harm a nursing baby. Consult your doctor before breast-feeding.

Our E.E.S. (erythromycin ethylsuccinate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Erythromycin Ethylsuccinate in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • severe dizziness, fainting, fast or pounding heartbeats;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • diarrhea that is watery or bloody;
  • hearing problems;
  • vomiting or fussiness after eating (in a child taking erythromycin); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • mild nausea, vomiting, diarrhea, or stomach pain;
  • dizziness, headache, feeling tired;
  • vaginal itching or discharge; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Erythromycin Ethylsuccinate (Erythromycin Ethylsuccinate) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Erythromycin Ethylsuccinate FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Symptoms of hepatitis, hepatic dysfunction and/or abnormal liver function test results may occur. (See WARNINGS.)

Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment. (See WARNINGS.)

Erythromycin has been associated with QT prolongation and ventricular arrhythmias, including ventricular tachycardia and torsades de pointes.

Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens- (erythromycin ethylsuccinate) Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.

There have been rare reports of pancreatitis and convulsions.

There have been isolated reports of reversi (erythromycin ethylsuccinate) ble hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.

Read the entire FDA prescribing information for Erythromycin Ethylsuccinate (Erythromycin Ethylsuccinate) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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