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Erythromycin Ethylsuccinate

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Erythromycin Ethylsuccinate Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

E.E.S. (erythromycin ethylsuccinate) is used to treat many different types of infections caused by bacteria. It is in a group of drugs called macrolide antibiotics. This medication is available in generic form. Common side effects include nausea, vomiting, abdominal pain, diarrhea, dizziness, headache, feeling tired, vaginal itching or discharge, or mild itching or skin rash.

The usual adult dose of erythromycin ethylsuccinate is 400 mg every 6 hours. Dosage may be increased up to 4 g per day according to the severity of the infection. The pediatric dose in mild to moderate infections is 30 to 50 mg/kg/day in equally divided doses every 6 hours. Erythromycin ethylsuccinate may interact with bromocriptine, cilostazol, cyclosporinem, digoxin, disopyramide, quinidine, sildenafil, tacrolimus, theophylline, verapamil, vinblastine, alprazolam or triazolam, blood thinners, carbamazepine, phenytoin, valproic acid, cholesterol-lowering medication, ergotamine, dihydroergotamine, or other antibiotics. Tell your doctor all medications you are taking. Erythromycin ethylsuccinate is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication can pass into breast milk and may harm a nursing baby. Consult your doctor before breast-feeding.

Our E.E.S. (erythromycin ethylsuccinate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Erythromycin Ethylsuccinate in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • severe dizziness, fainting, fast or pounding heartbeats;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • diarrhea that is watery or bloody;
  • hearing problems;
  • vomiting or fussiness after eating (in a child taking erythromycin); or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • mild nausea, vomiting, diarrhea, or stomach pain;
  • dizziness, headache, feeling tired;
  • vaginal itching or discharge; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Erythromycin Ethylsuccinate (Erythromycin Ethylsuccinate) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Erythromycin Ethylsuccinate Overview - Patient Information: Side Effects

SIDE EFFECTS: Nausea, vomiting, diarrhea, stomach pain/cramping, and loss of appetite may occur. Taking this medication with food may lessen these symptoms. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: signs of liver disease (such as persistent nausea/vomiting, yellowing eyes or skin, dark urine, severe stomach/abdominal pain), unusual tiredness, muscle weakness, slurred speech, blurred vision, drooping eyelids, hearing loss.

Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/irregular heartbeat.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because these products may make them worse.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Erythromycin Ethylsuccinate (Erythromycin Ethylsuccinate)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Erythromycin Ethylsuccinate FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Symptoms of hepatitis, hepatic dysfunction and/or abnormal liver function test results may occur. (See WARNINGS.)

Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment. (See WARNINGS.)

Erythromycin has been associated with QT prolongation and ventricular arrhythmias, including ventricular tachycardia and torsades de pointes.

Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens- (erythromycin ethylsuccinate) Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.

There have been rare reports of pancreatitis and convulsions.

There have been isolated reports of reversi (erythromycin ethylsuccinate) ble hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.

Read the entire FDA prescribing information for Erythromycin Ethylsuccinate (Erythromycin Ethylsuccinate) »

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EryPed - User Reviews

EryPed User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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