Evoclin

EVOCLIN®
(clindamycin phosphate)

DRUG DESCRIPTION

EVOCLIN (clindamycin phosphate) Foam contains clindamycin (1%) as clindamycin phosphate.

Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic, lincomycin.

The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

 EVOCLIN® (clindamycin phosphate) Structural Formula Illustration

Molecular Formula: C18H34ClN2O8PS      Molecular Weight: 504.97 g/mol

EVOCLIN Foam contains clindamycin (1%) as clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per gram in a thermolabile hydroethanolic foam vehicle consisting of cetyl alcohol, ethanol (58%), polysorbate 60, potassium hydroxide, propylene glycol, purified water, and stearyl alcohol pressurized with a hydrocarbon (propane/butane) propellant.

What are the possible side effects of clindamycin topical (Cleocin T, Clindagel, ClindaMax, ClindaReach Pledget, Evoclin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when clindamycin is applied to the skin, side effects can occur if the medication is absorbed into your bloodstream.

Stop using clindamycin topical and call your doctor at once if you have any of these serious side effects:

  • severe redness, itching, or dryness of treat skin areas;...

Read All Potential Side Effects and See Pictures of Evoclin »

Last reviewed on RxList: 2/9/2012
This monograph has been modified to include the generic and brand name in many instances.

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