Evoclin (Clindamycin Phosphate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

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Evoclin

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EVOCLIN®
(clindamycin phosphate)

DRUG DESCRIPTION

EVOCLIN (clindamycin phosphate) Foam contains clindamycin (1%) as clindamycin phosphate.

Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic, lincomycin.

The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

EVOCLIN® (clindamycin phosphate) Structural Formula Illustration

Molecular Formula: C₁₈H₃₄ClN₂O₈PS Molecular Weight: 504.97 g/mol

EVOCLIN Foam contains clindamycin (1%) as clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per gram in a thermolabile hydroethanolic foam vehicle consisting of cetyl alcohol, ethanol (58%), polysorbate 60, potassium hydroxide, propylene glycol, purified water, and stearyl alcohol pressurized with a hydrocarbon (propane/butane) propellant.

What are the possible side effects of clindamycin topical (Cleocin T, Clindagel, ClindaMax, ClindaReach Pledget, Evoclin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have any of these serious side effects:

severe redness, itching, or dryness of treat skin areas; or
diarrhea that is watery or bloody.

Less serious side effects may include:

mild burning or...

Read All Potential Side Effects and See Pictures of Evoclin »

What are the precautions when taking clindamycin phosphate (Evoclin)?

Before using clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: chronic asthma or hay fever (atopic conditions), intestinal diseases (e.g., ulcerative colitis, enteritis).

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if the medication in this product passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before...

Read All Potential Precautions of Evoclin »

Last reviewed on RxList: 2/9/2012
This monograph has been modified to include the generic and brand name in many instances.