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Exforge
Angiotensin Receptor Blockers (ARBs) »
What are angiotensin receptor blockers (ARBs) and how do they work?
The class of drugs called angiotensin receptor blockers (ARBs), as the class name suggests, are drugs that block the action of angiotensin. Specifically, ARBs prevent angiotensin II from binding to the angiotensin II receptor on blood vessels and other tissues.
Angiotensin II is a very potent chemical that causes the muscles surrounding blood vessels to contract, thereby narrowing the blood vessels. Narrowing of blood vessels increases the pressure within the blood vessels and may lead to high blood pressure (hypertension). Reducing the binding and activity of angiotensin II leads to widening (dilation) of blood vessels and reduces blood pressure. By lowering blood pressure against which the heart must pump, the amount of work that the heart must do is reduced. ACE inhibitors also reduce blood pressure in the kidneys, slowing the progression of kidney disease due to high b...
Exforge
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Exforge Drug Center
Medical Editor: John P. Cunha, DO, FACOEP
Exforge (amlodipine and valsartan) is used to treat high blood pressure (hypertension). This medication is usually given after others have been tried without successful treatment of hypertension. Exforge is a combination of amlodipine, which is in a group of drugs called calcium channel blockers, and valsartan is in a group of drugs called angiotensin II receptor antagonists. Common side effects include dizziness or lightheadedness as your body adjusts to the medication. Runny/stuffy nose or flushing may also occur.
Exforge is available in dosage strengths ranging from amlodipine/valsartan 5/160 mg tablets to 10/320 mg tablets. Exforge may interact with heart medication, potassium supplements or salt substitutes, diuretics (water pills), or other medications that lower blood pressure. Tell your doctor all medications you are taking. Exforge is not recommended for use during pregnancy due to the risk for harm to a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Our Exforge (amlodipine and valsartan) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Exforge Prescribing Information: Indications & Dosage
Hypertension
Exforge (amlodipine and valsartan) is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including amlodipine and the ARB class to which valsartan principally belongs. There are no controlled trials demonstrating risk reduction with Exforge.
Control of high blood pressure sh...
Read the complete drug monograph for Exforge »
What is Exforge Prescribing Information?
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Exforge Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, amlodipine and valsartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.
Call your doctor at once if you have any other serious side effects, such as:
- feeling like you might p...
Read the complete patient information for Exforge »
What is Exforge Patient Information?
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Exforge Consumer Information: Uses
This product is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
This product contains 2 medications, amlodipine and valsartan. Amlodipine is a calcium channel blocker, and valsartan is an angiotensin receptor blocker. They both work differently to relax the blood vessels so that blood can flow through the body more easily.
These medications are used together when one drug is not controlling your blood pressure. Your doctor may direct you to start taking the individual medications first, and then swi...
Read the complete consumer information for Exforge »
What is Exforge Consumer Information?
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
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Additional Exforge Information
Exforge - User Reviews
Exforge User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Exforge sorted by most helpful.
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