"The U.S. Food and Drug Administration yesterday approved Rixubis [Coagulation Factor IX (Recombinant)] for use in people with hemophilia B who are 16 years of age and older. Rixubis is indicated for the control and prevention of bleeding episodes"...
Exjade Consumer (continued)
This drug should not be used with the following medication because very serious interactions may occur: other medications that remove iron from your body (e.g., deferoxamine).
If you are currently using the medication listed above, tell your doctor or pharmacist before starting deferasirox.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antacids, cholestyramine, repaglinide, any form of vitamin/mineral supplement.
Other medications can affect the removal of deferasirox from your body, which may affect how deferasirox works. Examples include rifamycins (such as rifabutin), drugs used to treat seizures (such as phenobarbital, phenytoin), among others.
Other medications may increase your risk for stomach/intestinal bleeding and ulcers when taken with deferasirox. Tell your doctor or pharmacist about all the medications you use, including: bisphosphonates taken by mouth (e.g., alendronate), "blood thinners" (e.g., anticoagulants such as heparin, warfarin), corticosteroids (e.g., prednisone).
Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that may increase your risk of stomach/intestinal bleeding and ulcers if taken with deferasirox. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Ask your doctor or pharmacist for more details.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: Do not share this medication with others.
Laboratory and/or medical tests (e.g., serum ferritin, blood counts, liver and kidney function tests, vision and hearing tests, liver iron concentration) will be performed before starting and while you are receiving treatment with this medication to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised March 2013. Copyright(c) 2013 First Databank, Inc.
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