"An expert panel has recommended expanded adoption of the drug hydroxyurea for the care of people with sickle cell disease, according to a report issued today. The report also suggests that clinicians give periodic blood transfusions to children w"...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
DEFERASIROX TABLET - FOR ORAL SUSPENSION
COMMON BRAND NAME(S): Exjade
WARNING: Deferasirox may rarely cause serious (even fatal) kidney disease, liver disease, and stomach/intestinal bleeding (see also Side Effects section). Kidney disease may be more likely to occur in people with kidney problems and in people with serious blood diseases. Liver disease may be more likely to occur in people with liver problems (such as cirrhosis) and in older adults. Stomach/intestinal bleeding may be more likely to occur in older adults with serious blood diseases (including blood cancers). Consult your doctor for more details.
Your doctor will monitor you closely while you are taking this medication. Keep all regular medical and laboratory appointments.
USES: This medication is used to treat ongoing high levels of iron in the body caused by multiple blood transfusions. It is also used to treat high levels of iron in patients with a certain blood disorder who do not require blood transfusions (non-transfusion dependent thalassemia). Deferasirox can be taken by mouth and belongs to a class of drugs known as iron chelating agents. It works by reacting with iron, allowing the body to pass extra iron out in the stool.
Frequent blood transfusions are often needed in certain types of blood diseases (e.g., sickle cell disease, anemia). Blood transfusions have very helpful benefits, but they can cause the body to hold on to too much iron. For patients who receive multiple blood transfusions and for patients who have non-transfusion dependent thalassemia but high iron levels, extra iron can build up in various organs and cause problems such as heart failure, liver disease and diabetes. Getting rid of extra iron can decrease the risk of these diseases.
HOW TO USE: Stir the tablet(s) into water, orange juice or apple juice until the tablets have completely broken apart and are well mixed into the liquid. If your dose is less than 1 gram, stir the tablets into about 1/2 cup (3.5 ounces) of liquid. If your dose is more than 1 gram, use about 1 cup (7 ounces) of liquid. Drink all of the mixture immediately, then add more liquid to the empty container and stir to get any drug that may remain. Drink all of this rinsing liquid immediately.
Take this medication on an empty stomach at least 30 minutes before food, usually once daily or as directed by your doctor. Do not chew the tablets or swallow them whole. Always mix this medication into liquid as directed.
Certain antacids that contain aluminum may decrease the amount of medication that your body can absorb. If you take an antacid, wait at least 2 hours after taking this medication.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Dosage is based on your medical condition, body size and response to therapy. Your dosage may need to be lowered or your treatment may need to be stopped if you get certain side effects. Follow your doctor's instructions carefully.
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