Exjade
FDA Approves Octaplas to Treat Blood Clotting Disorders »
"The U.S. Food and Drug Administration today approved Octaplas, a pooled plasma (human) blood product for the replacement of clotting proteins (coagulation factors) in certain medical conditions where patients have insufficient levels. Clotting pr"...
Read the FDA Approves Octaplas to Treat Blood Clotting Disorders article »
Exjade
OVERDOSE
Cases of overdose (2-3 times the prescribed dose for several weeks) have been reported. In one case, this resulted in hepatitis which resolved without long-term consequences after a dose interruption. Single doses up to 80 mg per kg per day in iron overloaded β-thalassemic patients have been tolerated with nausea and diarrhea noted. In healthy volunteers, single doses of up to 40 mg per kg per day were tolerated. There is no specific antidote for Exjade. In case of overdose, induce vomiting and employ gastric lavage.
CONTRAINDICATIONS
Exjade is contraindicated in patients with:
- Serum creatinine greater than 2 times the age-appropriate upper limit of normal or creatinine clearance less than 40 mL/min or [see WARNING AND PRECAUTIONS];
- Poor performance status;
- High-risk myelodysplastic syndromes;
- Advanced malignancies;
- Platelet counts < 50 x 109/L;
- Known hypersensitivity to deferasirox or any component of Exjade [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS].
Last reviewed on RxList: 2/5/2013
This monograph has been modified to include the generic and brand name in many instances.
Additional Exjade Information
Exjade - User Reviews
Exjade User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Exjade sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Women's Health
Find out what women really need.
Updated & New
