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Exjade

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Exjade

Exjade Patient Information including If I Miss a Dose

What happens if I miss a dose (Exjade)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Exjade)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking deferasirox (Exjade)?

While you are taking deferasirox, do not take antacids that contain aluminum, such as Amphojel, Gaviscon, Maalox, Mi-Acid, Mylanta, Rulox, and others.

Do not use other iron chelating medicines such as deferoxamine (Desferal), unless your doctor has told you to.

Deferasirox may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What other drugs will affect deferasirox (Exjade)?

Many drugs can interact with deferasirox. Below is just a partial list. Tell your doctor if you are using:

  • alendronate (Fosamax), etidronate (Didronel), ibandronate (Boniva), pamidronate (Aredia), risedronate (Actonel), or zoledronic acid (Reclast, Zometa);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), rifampin (Rifater, Rifadin, Rifamate), telithromycin (Ketek), and others;
  • birth control pills;
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • cancer medication such as paclitaxel (Taxol) or tamoxifen (Soltamox);
  • cholesterol-lowering drugs such as cholestyramine (Prevalite, Questran), atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), or simvastatin (Zocor, Simcor, Vytorin);
  • heart or blood pressure medications such as amiodarone (Cordarone, Pacerone), amlodipine (Norvasc, Lotrel), carvedilol (Coreg), diltiazem (Cartia, Cardizem), felodipine (Plendil), losartan (Hyzaar, Cozaar), nifedipine (Adalat), nisoldipine (Sular), torsemide (Demadex), or verapamil (Calan, Covera, Isoptin);
  • heart rhythm medication such as quinidine (Quin-G);
  • HIV medicines such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), saquinavir (Invirase), and others;
  • medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune) or tacrolimus (Prograf);
  • montelukast (Singulair) or zafirlukast (Accolate);
  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others;
  • a sedative such as alprazolam (Xanax), diazepam (Valium), midazolam (Versed), or triazolam (Halcion);
  • seizure medications such as fosphenytoin (Cerebyx) or phenytoin (Dilantin);
  • steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;
  • sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others); or
  • type 2 diabetes medications such as glimepiride (Amaryl), glipizide (Glucotrol), nateglinide (Starlix), pioglitazone (Actos, Actoplus Met), repaglinide (Prandin), rosiglitazone (Avandia, Avandamet), or tolbutamide (Orinase).

This list is not complete and there are many other medicines that can interact with deferasirox. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about deferasirox.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 6.01. Revision date: 7/7/2011.

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