"The U.S. Food and Drug Administration today approved a new use for Jakafi (ruxolitinib) to treat patients with polycythemia vera, a chronic type of bone marrow disease. Jakafi is the first drug approved by the FDA for this condition.
Exjade Patient Information including How Should I Take
In this Article
- What is deferasirox (Exjade)?
- What are the possible side effects of deferasirox (Exjade)?
- What is the most important information I should know about deferasirox (Exjade)?
- What should I discuss with my healthcare provider before using deferasirox (Exjade)?
- How should I take deferasirox (Exjade)?
- What happens if I miss a dose (Exjade)?
- What happens if I overdose (Exjade)?
- What should I avoid while taking deferasirox (Exjade)?
- What other drugs will affect deferasirox (Exjade)?
- Where can I get more information?
What should I discuss with my healthcare provider before using deferasirox (Exjade)?
You should not use this medication if you are allergic to it, or if you have:
- severe kidney disease;
- advanced cancer;
- a blood cell disorder such as anemia (lack of red blood cells) or low levels of platelets in your blood; or
- if you are also using theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl).
To make sure you can safely use deferasirox, tell your doctor if you have any of these other conditions:
- kidney disease;
- liver disease;
- cancer (especially blood cell cancer such as leukemia);
- a history of stomach or intestinal bleeding;
- vision or hearing problems; or
- a weak immune system caused by disease (such as cancer, HIV, or AIDS), or by receiving steroids, chemotherapy, or radiation.
FDA pregnancy category C. It is not known whether deferasirox will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether deferasirox passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking deferasirox.
Serious side effects may be more likely in older adults taking deferasirox.
How should I take deferasirox (Exjade)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Take deferasirox on an empty stomach at least 30 minutes before eating. Take the medication at the same time every day.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. Drink plenty of fluids while taking deferasirox to keep from getting dehydrated.
Do not chew, crush, or swallow the deferasirox tablet whole. Place it into a glass of apple juice, orange juice, or water and allow the tablet to disperse in the liquid. The tablet will not dissolve completely. Drink this mixture right away. To make sure you get the entire dose, add a little more liquid to the same glass, swirl gently and drink right away.
If you take less than 1000 milligrams (1 gram) daily, dissolve the deferasirox tablets in about one-half cup of apple juice, orange juice, or water. If you take more than 1000 milligrams daily, dissolve the tablets in about 1 cup of apple juice, orange juice, or water.
To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.
Store at room temperature, away from moisture and heat.
Additional Exjade Information
- Exjade Drug Interactions Center: deferasirox oral
- Exjade Side Effects Center
- Exjade Overview including Precautions
- Exjade FDA Approved Prescribing Information including Dosage
Exjade - User Reviews
Exjade User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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