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home > drugs a-z list > extraneal (icodextrin peritoneal dialysis solution) drug center > extraneal (icodextrin peritoneal dialysis solution) drug - overdosage and contraindications
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Extraneal
What are the kidneys?
The kidneys play key roles in body function, not only by filtering the blood and getting rid of waste products, but also by balancing levels of electrolyte levels in the body, controlling blood pressure, and stimulating the production of red blood cells.
The kidneys are located in the abdomen toward the back, normally one on each side of the spine. They get their blood supply through the renal arteries directly from the aorta and send blood back to the heart via the renal veins to the vena cava. (The term "renal" is derived from the Latin name for kidney.)
The kidneys have the ability to monitor the amount of body fluid, the concentrations of electrolytes like sodium and potassium, and the acid-base balance of the body. They filter waste products of body metabolism, like urea from protein metabolism and uric acid from DNA breakdown. Two waste products in the blood can be measured: blood urea nitrogen (BUN) ...
Extraneal
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OVERDOSE
No data are available on experiences of overdosage with Extraneal (icodextrin peritoneal dialysis solution) . Overdosage of Extraneal would be expected to result in higher levels of serum icodextrin and metabolites, but it is not known what signs or symptoms might be caused by exposure in excess of the exposures used in clinical trials. In the event of overdosage with Extraneal (icodextrin peritoneal dialysis solution) , continued peritoneal dialysis with glucose-based solutions should be provided.
CONTRAINDICATIONS
Extraneal (icodextrin) is contraindicated in patients with a known allergy to cornstarch or icodextrin, in patients with maltose or isomaltose intolerance, in patients with glycogen storage disease, and in patients with pre-existing severe lactic acidosis.
Last reviewed on RxList: 4/29/2011
This monograph has been modified to include the generic and brand name in many instances.
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