Faslodex (Fulvestrant) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Faslodex

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Breast cancer is the most common cancer among American women.
One in every eight women in the United States develops breast cancer.
There are many types of breast cancer that differ in their capability of spreading (metastasize) to other body tissues.
The causes of breast cancer are not yet fully known although a number of risk factors have been identified.
There are many different types of breast cancer.
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Treatment of breast cancer depends on the type of cancer and its stage (the extent of spread in the body).

According to the American Cancer society:

Over 200,000 new cases of invasive breast cancer are diagnosed each year.
Nearly 40,000 women will die of breast cancer in 2011.
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Faslodex

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FASLODEX®
(fulvestrant) Injection

DRUG DESCRIPTION

FASLODEX® (fulvestrant) Injection for intramuscular administration is an estrogen receptor antagonist. The chemical name is 7-alpha-[9-(4,4,5,5,5-penta fluoropentylsulphinyl) nonyl]estra-1,3,5-(10)- triene-3,17beta-diol. The molecular formula is C₃₂H₄₇F₅O₃S and its structural formula is:

FASLODEX® (fulvestrant) Structural Formula Illustration

Fulvestrant is a white powder with a molecular weight of 606.77. The solution for injection is a clear, colorless to yellow, viscous liquid.

Each injection contains as inactive ingredients: 10% w/v Alcohol, USP, 10% w/v Benzyl Alcohol, NF, and 15% w/v Benzyl Benzoate, USP, as co-solvents, and made up to 100% w/v with Castor Oil, USP as a co-solvent and release rate modifier

What are the possible side effects of fulvestrant (Faslodex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

headache, back pain;
nausea, vomiting, stomach pain;
constipation, diarrhea;
sore throat, cough;
weakness;
warmth, redness, or tingly feeling under your skin;
loss of appetite;
swelling in your hands or feet;
unusual vaginal...

Read All Potential Side Effects and See Pictures of Faslodex »

What are the precautions when taking fulvestrant (Faslodex)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: bleeding problems, low platelet counts (thrombocytopenia), current treatment with "blood thinners" (e.g., warfarin).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness...

Read All Potential Precautions of Faslodex »

Last reviewed on RxList: 6/3/2011
This monograph has been modified to include the generic and brand name in many instances.