"Substituting nanoparticle albumin-bound paclitaxel (nab-paclitaxel) for solvent-based paclitaxel when treating metastatic breast cancer increases the proportion of patients achieving pathological complete response after anthracycline-based chemot"...
(fulvestrant) Intramuscular Injection
FASLODEX® (fulvestrant) injection for intramuscular administration is an estrogen receptor antagonist. The chemical name is 7-alpha-[9-(4,4,5,5,5-penta fluoropentylsulphinyl) nonyl]estra-1,3,5-(10)- triene-3,17-beta-diol. The molecular formula is C32H47F5O3S and its structural formula is:
Fulvestrant is a white powder with a molecular weight of 606.77. The solution for injection is a clear, colorless to yellow, viscous liquid.
Each injection contains as inactive ingredients: 10% w/v Alcohol, USP, 10% w/v Benzyl Alcohol, NF, and 15% w/v Benzyl Benzoate, USP, as co-solvents, and made up to 100% w/v with Castor Oil, USP as a co-solvent and release rate modifier.
What are the possible side effects of fulvestrant (Faslodex)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- headache, back pain;
- bone pain, joint pain, muscle pain;
- vomiting, loss of appetite, constipation;
- weakness, feeling tired;
- cough, trouble breathing;
- pain in your arms or legs;
- hot flashes; or
- pain where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your...
What are the precautions when taking fulvestrant (Faslodex)?
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: bleeding problems, low platelet counts (thrombocytopenia), current treatment with "blood thinners" (e.g., warfarin).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness...
Last reviewed on RxList: 3/9/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Faslodex Information
Faslodex - User Reviews
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